The Cannabinoid 1 Receptor (CNR1) 1359 G/A Polymorphism Modulates Susceptibility to Ulcerative Colitis and the Phenotype in Crohn's Disease (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/arti...tool=pmcentrez
The endocannabinoid system links gut microbiota to adipogenesis (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925525/
Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus. (full – 2010) http://onlinelibrary.wiley.com/doi/1...09.01419.x/pdf
European Patent Application EP2044935- A composition containing non-psychotropic cannabinoids for the treatment of inflammatory diseases (full – 2010) http://www.freepatentsonline.com/EP2044935A1.html
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. (full - 2010)http://jpet.aspetjournals.org/content/335/1/92.full
Cannabinoids and the gut: New developments and emerging concepts. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20117132
Gut feelings about the endocannabinoid system (full – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01689.x/full
Treatment of Crohn's disease with cannabis: an observational study. (full – 2011) http/www.ima.org.il/FilesUpload/IMAJ/0/39/19985.pdf
Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?toolubmed
Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. (full – 2011) http/www.nature.com/ajg/journal/v106/n1/pdf/ajg2010305a.pdf
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (full – 2011) http/www.fasebj.org/content/25/8/2711.long
ENDOGENOUS CANNABINOID SYSTEM REGULATES INTESTINAL BARRIER FUNCTION IN VIVO THROUGH CANNABINOID TYPE 1 RECEPTOR ACTIVATION (full – 2011) http/ajpgi.physiology.org/content/early/2011/11/28/ajpgi.00158.2011.full-text.pdf+html
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (full – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01742.x/full
US Patent 7884133 B2 Cannabidiol derivatives such as 3-(2,6-dihydroxy-4-pentylphenyl)-4-prop-1-en-2-ylcyclohexene-1-carboxylic acid, used as as analgesics, antiinflammatory and antidiarrheal agents (full – 2011) https/www.google.com/patents/US7884133?dqatent+7884133&hl=en&sa=X&ei=Ujb0U_6EEIW5ogSl84LYDg&ved=0CB4Q6AEwAA
Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21726418
Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21876860
The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011) http/www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_acid_and_cannabidiol_ on_contractility_of_the_gastrointestinal_tract_of_ Suncus_murinus_
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21921665
Inhibition of cannabinoid metabolic enzymes reduces NSAID-induced gastric pathology (abst – 2011) http/www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/807.1?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21745190
Cannabinoid HU210 Protects Isolated Rat Stomach against Impairment Caused by Serum of Rats with Experimental Acute Pancreatitis. (full - 2012) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052921
The Gastrointestinal Pharmacology of Cannabinoids: Focus on Motility. (full – 2012) http/content.karger.com/produktedb/produkte.asp?DOI=000339072&typdf
The JNK inhibitor XG-102 protects against TNBS-induced colitis. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3302790/
Gut microbiota and the development of obesity. (full – 2012) http/scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112012000500007&lng=en&nrm=iso&tlng=en
Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice (full – 2012) http/www.jleukbio.org/content/91/6/911.full
The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness (full – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01954.x/full
Endocannabinoid modulation of jejunal afferent responses to LPS (full – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01961.x/full
Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility. (full – 2012) http/www.jneurosci.org/content/32/30/10331.long
Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3548934/
Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3372737/
Genetic Epidemiology and Pharmacogenetics in Irritable Bowel Syndrome. (full - 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3362100/
Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3417459/
Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22269477
The Cannabinoid Receptor type 2 Q63R variant increases the risk of celiac disease: Implication for a novel molecular biomarker and future therapeutic intervention. (abst – 2012) http/www.sciencedirect.com/science/article/pii/S1043661812000540
The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22917662
Agents that act luminally to treat diarrhoea and constipation. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22945441
Does Medical Marijuana Help Treat Diarrhea? (news – 2012) http/www.theweedblog.com/does-medical-marijuana-help-treat-diarrhea/
Marijuana might be able to treat your terrible case of the runs (news – 2012) http/www.thctotalhealthcare.com/tag/treat/
The Dual Effect of Cannabinoid Receptor-1 Deficiency on the Murine Postoperative Ileus (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067427
Altered expression of type-1 and type-2 cannabinoid receptors in celiac disease. (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062078
Role of endogenous cannabinoid system in the gut. (full - 2013) http/www.actaps.com.cn/qikan/manage/wenzhang/2013-4-12.pdf
Effect of high fat-diet and obesity on gastrointestinal motility. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3890396/
Cannabis Finds Its Way into Treatment of Crohn's Disease. (full – 2013) http/www.karger.com/Article/Pdf/356512
Irritable Bowel Syndrome and Migraine: Bystanders or Partners? (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3714407/
Cannabinoid Receptor 1 Gene and Irritable Bowel Syndrome: Phenotype and Quantitative Traits. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3602676/
Endocannabinoid and Cannabinoid-Like Fatty Acid Amide Levels Correlate with Pain-Related Symptoms in Patients with IBS-D and IBS-C: A Pilot Study. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3874007/
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract. (full – 2013) http/www.jpp.krakow.pl/journal/archive/04_13/pdf/167_04_13_article.pdf
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3677091/
Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3657109/
A potential role for GPR55 in gastrointestinal functions. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3660623/
Industrial hemp decreases intestinal motility stronger than indian hemp in mice. (link to PDF – 2013) http/www.europeanreview.org/article/3266
Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: The relevance of cannabinoid system. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23454360
Cannabis Induces a Clinical Response in Patients with Crohn's Disease: a Prospective Placebo-Controlled Study. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23648372
Interrogating Therapeutic Manipulation of the Endocannabinoid System in Human Colon (abst – 2013) http/www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/1123.1?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23706402
Acute Δ9-tetrahydrocannabinol blocks gastric hemorrhages induced by the nonsteroidal anti-inflammatory drug diclofenac sodium in mice. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23769745
3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23849204
Angiotensin II-induced activation of central AT1 receptors exerts endocannabinoidmediated gastroprotective effect in rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24145131
Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca(2+) channels of colonic smooth muscle cells in rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23972358
Interleukin 17A evoked mucosal damage is attenuated by cannabidiol and anandamide in a human colonic explant model. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24238999
Inhibition of fatty acid amide hydrolase (FAAH) as a novel therapeutic strategy in the treatment of pain and inflammatory diseases in the gastrointestinal tract (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24275607
Decreased Enteric Fatty Acid Amide Hydrolase Activity is Associated with Colonic Inertia in Slow Transit Constipation (abst – 2013) http/onlinelibrary.wiley.com/doi/10.1111/jgh.12346/abstract
Marijuana use patterns among patients with inflammatory bowel disease. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24185313
The cannabinoid-1 receptor inverse agonist taranabant reduces abdominal pain and increases intestinal transit in mice. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23692073
Still Believe Nature Got It Wrong? Top 10 Health Benefits of Marijuana (news – 2013) http/www.wakingtimes.com/2013/05/01/still-believe-nature-got-it-wrong-top-10-health-benefits-ofmarijuana/
Study: Cannabinoid Could Potentially Cut Down On NSAID-Induced Hospitalizations (news – 2013) http/blog.norml.org/2013/06/20/study-cannabinoid-could-potentially-cut-down-on-nsaid-inducedhospitalizations/
Herbal medicine may ease constipation (news – 2013) http/www.lifescript.com/health/centers/pain/alternative_treatments/traditional_chinese_herbal_medicine_articles/herbal_medicine_may_ease_constipation.aspx
Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epithelium. (full – 2014) http/ajpgi.physiology.org/content/307/2/G140
(Mo1121) Cannabinoid Use Decreases ED Utilization in a Gastroenterology Clinic Population (abst – 2014) http/www.gastrojournal.org/article/S0016-5085%2814%2962037-0/pdf
(Mo1122) Prevalence and Characterization of Cannabinoid Use in Patients With Gastrointestinal Disorders (abst – 2014) http/www.gastrojournal.org/article/S0016-5085%2814%2962037-0/pdf
Modulation of Gut-Specific Mechanisms by Chronic Δ9-THC Administration in Male Rhesus Macaques Infected with Simian Immunodeficiency Virus: A Systems Biology Analysis. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24400995
Association of cannabinoid type 1 receptor and fatty acid amide hydrolase genetic polymorphisms in Chinese patients with irritable bowel syndrome. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24444427
Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24460851
Toward modulation of the endocannabinoid system for treatment of gastrointestinal disease: FAAHster but not "higher". (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24641009
Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24631413
Vagal anandamide signaling via cannabinoid receptor 1 contributes to luminal 5-HT modulation of visceral nociception in rats. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24813296
Ultramicronized palmitoylethanolamide normalizes intestinal motility in a murine model of post-inflammatory accelerated transit: involvement of CB1 receptors and TRPV1. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24818658
Palmitoylethanolamide Regulates Development of Intestinal Radiation Injury in a Mast Cell-Dependent Manner. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24848354
The endocannabinoid anandamide regulates the peristaltic reflex by reducing neuroneuronal and neuro-muscular neurotransmission in ascending myenteric reflex pathways in rats. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24911079
Potential therapeutic applications of cannabinoids in gastrointestinal and liver diseases: Focus on Δ9-tetrahydrocannabinol pharmacology (abst – 2014) http/onlinelibrary.wiley.com/doi/10.1002/9781118451281.ch7/summary
Palmitoylethanolamide, a naturally-occurring lipid, is an orally effective intestinal anti-inflammatory agent (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25205418
Medical Marijuana for Digestive Disorders: High Time to Prescribe? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25199471
Gut microbiota and obesity: Role in aetiology and potential therapeutic target (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25194177
Epigenetic Regulation of Genes that Modulate Chronic Stress-induced Visceral Pain in the Peripheral Nervous System. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25263804
Cannabinoids Alleviate Experimentally Induced Intestinal Inflammation by Acting at Central and Peripheral Receptors (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25275313
Acute Activation of Cannabinoid Receptors by Anandamide Reduces Gastro-Intestinal Motility and Improves Postprandial Glycemia in Mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25281429
Colitis generates remote antinociception in rats: the role of the L arginine/NO/cGMP/PKG/KATP pathway and involvement of cannabinoid and opioid systems (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25286904
Chronic administration of Δ9-tetrahydrocannabinol induces intestinal anti-inflammatory microRNA expression during acute SIV infection of rhesus macaques (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25378491
N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N palmitoylethanolamine levels and counteracts murine colitis (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25384424
GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25348153
Role of orphan G protein-coupled receptor 55 in diabetic gastroparesis in mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24964851
Antibiotic-induced dysbiosis alters host-bacterial interactions and leads to colonic sensory and motor changes in mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25531553
Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent (full – 2015) http://onlinelibrary.wiley.com/doi/1...bph.12907/full
AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally-restricted manner (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25572435
A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25505251
No association between the functional cannabinoid receptor type 2 Q63R variants and inflammatory bowel disease in Turkish subjects (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25599774
The endocannabinoid system links gut microbiota to adipogenesis (full - 2010) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2925525/
Involvement of cannabinoid-1 and cannabinoid-2 receptors in septic ileus. (full – 2010) http://onlinelibrary.wiley.com/doi/1...09.01419.x/pdf
European Patent Application EP2044935- A composition containing non-psychotropic cannabinoids for the treatment of inflammatory diseases (full – 2010) http://www.freepatentsonline.com/EP2044935A1.html
Pharmacological effects of cannabinoids on the Caco-2 cell culture model of intestinal permeability. (full - 2010)http://jpet.aspetjournals.org/content/335/1/92.full
Cannabinoids and the gut: New developments and emerging concepts. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20117132
Gut feelings about the endocannabinoid system (full – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01689.x/full
Treatment of Crohn's disease with cannabis: an observational study. (full – 2011) http/www.ima.org.il/FilesUpload/IMAJ/0/39/19985.pdf
Cannabidiol Reduces Intestinal Inflammation through the Control of Neuroimmune Axis (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3232190/?toolubmed
Efficacy of a Chinese herbal proprietary medicine (Hemp Seed Pill) for functional constipation. (full – 2011) http/www.nature.com/ajg/journal/v106/n1/pdf/ajg2010305a.pdf
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
Increasing endogenous 2-arachidonoylglycerol levels counteracts colitis and related systemic inflammation. (full – 2011) http/www.fasebj.org/content/25/8/2711.long
ENDOGENOUS CANNABINOID SYSTEM REGULATES INTESTINAL BARRIER FUNCTION IN VIVO THROUGH CANNABINOID TYPE 1 RECEPTOR ACTIVATION (full – 2011) http/ajpgi.physiology.org/content/early/2011/11/28/ajpgi.00158.2011.full-text.pdf+html
A novel CB receptor GPR55 and its ligands are involved in regulation of gut movement in rodents. (full – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2011.01742.x/full
US Patent 7884133 B2 Cannabidiol derivatives such as 3-(2,6-dihydroxy-4-pentylphenyl)-4-prop-1-en-2-ylcyclohexene-1-carboxylic acid, used as as analgesics, antiinflammatory and antidiarrheal agents (full – 2011) https/www.google.com/patents/US7884133?dqatent+7884133&hl=en&sa=X&ei=Ujb0U_6EEIW5ogSl84LYDg&ved=0CB4Q6AEwAA
Cannabinoid actions at TRPV channels: effects on TRPV3 and TRPV4 and their potential relevance to gastrointestinal inflammation. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21726418
Alternative targets within the endocannabinoid system for future treatment of gastrointestinal diseases. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21876860
The effects of cannabidiolic acid and cannabidiol on contractility of the gastrointestinal tract of Suncus murinus. (abst – 2011) http/www.unboundmedicine.com/medline/ebm/record/21975813/abstract/The_effects_of_cannabidiolic_acid_and_cannabidiol_ on_contractility_of_the_gastrointestinal_tract_of_ Suncus_murinus_
Effects of Cannabinoid Agonists on Sheep Sphincter of Oddi in vitro. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21921665
Inhibition of cannabinoid metabolic enzymes reduces NSAID-induced gastric pathology (abst – 2011) http/www.fasebj.org/cgi/content/meeting_abstract/25/1_MeetingAbstracts/807.1?maxtoshow=&hits=80&RESULTFORMAT=&fulltext=cannabinoid&searchid=1&FIRSTINDEX=80&sortspec=date&resourcetype=HWCIT
Cannabinoids mediate opposing effects on inflammation-induced intestinal permeability. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21745190
Cannabinoid HU210 Protects Isolated Rat Stomach against Impairment Caused by Serum of Rats with Experimental Acute Pancreatitis. (full - 2012) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0052921
The Gastrointestinal Pharmacology of Cannabinoids: Focus on Motility. (full – 2012) http/content.karger.com/produktedb/produkte.asp?DOI=000339072&typdf
The JNK inhibitor XG-102 protects against TNBS-induced colitis. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3302790/
Gut microbiota and the development of obesity. (full – 2012) http/scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112012000500007&lng=en&nrm=iso&tlng=en
Effects of palmitoylethanolamide on intestinal injury and inflammation caused by ischemia-reperfusion in mice (full – 2012) http/www.jleukbio.org/content/91/6/911.full
The effects of fasting duration on gastric emptying in man, an exploration of the role of the endocannabinoid system and inter-individual responsiveness (full – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01954.x/full
Endocannabinoid modulation of jejunal afferent responses to LPS (full – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2982.2012.01961.x/full
Cannabinoid receptor 1 in the vagus nerve is dispensable for body weight homeostasis but required for normal gastrointestinal motility. (full – 2012) http/www.jneurosci.org/content/32/30/10331.long
Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3548934/
Inhibiting fatty acid amide hydrolase normalizes endotoxin-induced enhanced gastrointestinal motility in mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3372737/
Genetic Epidemiology and Pharmacogenetics in Irritable Bowel Syndrome. (full - 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3362100/
Inhibitory effect of cannabichromene, a major non-psychotropic cannabinoid extracted from Cannabis sativa, on inflammation-induced hypermotility in mice. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3417459/
Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22269477
The Cannabinoid Receptor type 2 Q63R variant increases the risk of celiac disease: Implication for a novel molecular biomarker and future therapeutic intervention. (abst – 2012) http/www.sciencedirect.com/science/article/pii/S1043661812000540
The endocannabinoid system in inflammatory bowel diseases: from pathophysiology to therapeutic opportunity. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22917662
Agents that act luminally to treat diarrhoea and constipation. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22945441
Does Medical Marijuana Help Treat Diarrhea? (news – 2012) http/www.theweedblog.com/does-medical-marijuana-help-treat-diarrhea/
Marijuana might be able to treat your terrible case of the runs (news – 2012) http/www.thctotalhealthcare.com/tag/treat/
The Dual Effect of Cannabinoid Receptor-1 Deficiency on the Murine Postoperative Ileus (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0067427
Altered expression of type-1 and type-2 cannabinoid receptors in celiac disease. (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0062078
Role of endogenous cannabinoid system in the gut. (full - 2013) http/www.actaps.com.cn/qikan/manage/wenzhang/2013-4-12.pdf
Effect of high fat-diet and obesity on gastrointestinal motility. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3890396/
Cannabis Finds Its Way into Treatment of Crohn's Disease. (full – 2013) http/www.karger.com/Article/Pdf/356512
Irritable Bowel Syndrome and Migraine: Bystanders or Partners? (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3714407/
Cannabinoid Receptor 1 Gene and Irritable Bowel Syndrome: Phenotype and Quantitative Traits. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3602676/
Endocannabinoid and Cannabinoid-Like Fatty Acid Amide Levels Correlate with Pain-Related Symptoms in Patients with IBS-D and IBS-C: A Pilot Study. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3874007/
Pro-resolution, protective and anti-nociceptive effects of a cannabis extract in the rat gastrointestinal tract. (full – 2013) http/www.jpp.krakow.pl/journal/archive/04_13/pdf/167_04_13_article.pdf
A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3677091/
Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3657109/
A potential role for GPR55 in gastrointestinal functions. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3660623/
Industrial hemp decreases intestinal motility stronger than indian hemp in mice. (link to PDF – 2013) http/www.europeanreview.org/article/3266
Preventive and therapeutic oral administration of the pentacyclic triterpene α,β-amyrin ameliorates dextran sulfate sodium-induced colitis in mice: The relevance of cannabinoid system. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23454360
Cannabis Induces a Clinical Response in Patients with Crohn's Disease: a Prospective Placebo-Controlled Study. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23648372
Interrogating Therapeutic Manipulation of the Endocannabinoid System in Human Colon (abst – 2013) http/www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/1123.1?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23706402
Acute Δ9-tetrahydrocannabinol blocks gastric hemorrhages induced by the nonsteroidal anti-inflammatory drug diclofenac sodium in mice. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23769745
3-Carboxamido-5-aryl-isoxazoles as new CB2 agonists for the treatment of colitis. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23849204
Angiotensin II-induced activation of central AT1 receptors exerts endocannabinoidmediated gastroprotective effect in rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24145131
Magnolol inhibits colonic motility through down-regulation of voltage-sensitive L-type Ca(2+) channels of colonic smooth muscle cells in rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23972358
Interleukin 17A evoked mucosal damage is attenuated by cannabidiol and anandamide in a human colonic explant model. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24238999
Inhibition of fatty acid amide hydrolase (FAAH) as a novel therapeutic strategy in the treatment of pain and inflammatory diseases in the gastrointestinal tract (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24275607
Decreased Enteric Fatty Acid Amide Hydrolase Activity is Associated with Colonic Inertia in Slow Transit Constipation (abst – 2013) http/onlinelibrary.wiley.com/doi/10.1111/jgh.12346/abstract
Marijuana use patterns among patients with inflammatory bowel disease. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24185313
The cannabinoid-1 receptor inverse agonist taranabant reduces abdominal pain and increases intestinal transit in mice. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23692073
Still Believe Nature Got It Wrong? Top 10 Health Benefits of Marijuana (news – 2013) http/www.wakingtimes.com/2013/05/01/still-believe-nature-got-it-wrong-top-10-health-benefits-ofmarijuana/
Study: Cannabinoid Could Potentially Cut Down On NSAID-Induced Hospitalizations (news – 2013) http/blog.norml.org/2013/06/20/study-cannabinoid-could-potentially-cut-down-on-nsaid-inducedhospitalizations/
Herbal medicine may ease constipation (news – 2013) http/www.lifescript.com/health/centers/pain/alternative_treatments/traditional_chinese_herbal_medicine_articles/herbal_medicine_may_ease_constipation.aspx
Cannabinoid-induced autophagy regulates suppressor of cytokine signaling (SOCS)-3 in intestinal epithelium. (full – 2014) http/ajpgi.physiology.org/content/307/2/G140
(Mo1121) Cannabinoid Use Decreases ED Utilization in a Gastroenterology Clinic Population (abst – 2014) http/www.gastrojournal.org/article/S0016-5085%2814%2962037-0/pdf
(Mo1122) Prevalence and Characterization of Cannabinoid Use in Patients With Gastrointestinal Disorders (abst – 2014) http/www.gastrojournal.org/article/S0016-5085%2814%2962037-0/pdf
Modulation of Gut-Specific Mechanisms by Chronic Δ9-THC Administration in Male Rhesus Macaques Infected with Simian Immunodeficiency Virus: A Systems Biology Analysis. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24400995
Association of cannabinoid type 1 receptor and fatty acid amide hydrolase genetic polymorphisms in Chinese patients with irritable bowel syndrome. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24444427
Selective inhibition of FAAH produces antidiarrheal and antinociceptive effect mediated by endocannabinoids and cannabinoid-like fatty acid amides. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24460851
Toward modulation of the endocannabinoid system for treatment of gastrointestinal disease: FAAHster but not "higher". (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24641009
Glucose metabolism: Focus on gut microbiota, the endocannabinoid system and beyond. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24631413
Vagal anandamide signaling via cannabinoid receptor 1 contributes to luminal 5-HT modulation of visceral nociception in rats. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24813296
Ultramicronized palmitoylethanolamide normalizes intestinal motility in a murine model of post-inflammatory accelerated transit: involvement of CB1 receptors and TRPV1. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24818658
Palmitoylethanolamide Regulates Development of Intestinal Radiation Injury in a Mast Cell-Dependent Manner. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24848354
The endocannabinoid anandamide regulates the peristaltic reflex by reducing neuroneuronal and neuro-muscular neurotransmission in ascending myenteric reflex pathways in rats. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24911079
Potential therapeutic applications of cannabinoids in gastrointestinal and liver diseases: Focus on Δ9-tetrahydrocannabinol pharmacology (abst – 2014) http/onlinelibrary.wiley.com/doi/10.1002/9781118451281.ch7/summary
Palmitoylethanolamide, a naturally-occurring lipid, is an orally effective intestinal anti-inflammatory agent (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25205418
Medical Marijuana for Digestive Disorders: High Time to Prescribe? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25199471
Gut microbiota and obesity: Role in aetiology and potential therapeutic target (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25194177
Epigenetic Regulation of Genes that Modulate Chronic Stress-induced Visceral Pain in the Peripheral Nervous System. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25263804
Cannabinoids Alleviate Experimentally Induced Intestinal Inflammation by Acting at Central and Peripheral Receptors (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25275313
Acute Activation of Cannabinoid Receptors by Anandamide Reduces Gastro-Intestinal Motility and Improves Postprandial Glycemia in Mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25281429
Colitis generates remote antinociception in rats: the role of the L arginine/NO/cGMP/PKG/KATP pathway and involvement of cannabinoid and opioid systems (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25286904
Chronic administration of Δ9-tetrahydrocannabinol induces intestinal anti-inflammatory microRNA expression during acute SIV infection of rhesus macaques (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25378491
N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N palmitoylethanolamine levels and counteracts murine colitis (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25384424
GPR18 is required for a normal CD8αα intestinal intraepithelial lymphocyte compartment (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25348153
Role of orphan G protein-coupled receptor 55 in diabetic gastroparesis in mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24964851
Antibiotic-induced dysbiosis alters host-bacterial interactions and leads to colonic sensory and motor changes in mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25531553
Palmitoylethanolamide, a naturally occurring lipid, is an orally effective intestinal anti-inflammatory agent (full – 2015) http://onlinelibrary.wiley.com/doi/1...bph.12907/full
AM841, a covalent cannabinoid ligand, powerfully slows gastrointestinal motility in normal and stressed mice in a peripherally-restricted manner (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25572435
A Gut Microbial Metabolite of Linoleic Acid, 10-Hydroxy-cis-12-octadecenoic Acid, Ameliorates Intestinal Epithelial Barrier Impairment Partially via GPR40-MEK-ERK Pathway (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25505251
No association between the functional cannabinoid receptor type 2 Q63R variants and inflammatory bowel disease in Turkish subjects (abst – 2015) http://www.ncbi.nlm.nih.gov/pubmed/25599774