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  • CANCER - LIVER

    The synthetic cannabinoid WIN 55,212-2 sensitizes hepatocellular carcinoma cells to tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced apoptosis by activating p8/CCAAT/enhancer binding protein homologous protein (CHOP)/death receptor 5 (DR5) axis. (full – 2010) http/molpharm.aspetjournals.org/content/77/5/854.long
    Recent advances in the understanding of the role of the endocannabinoid system in liver diseases. (full - 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3033442/
    The effect of the activation of cannabinoid receptor on the proliferation and apoptosis of hepatoma HepG2 cells (abst – 2010) http/www.ncbi.nlm.nih.gov/pubmed/20368112
    Membrane cholesterol mediates the endocannabinoids-anandamide affection on HepG2 cells (abst – 2010) http/www.ncbi.nlm.nih.gov/pubmed/20380798
    Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPKdependent activation of autophagy. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3131949/
    Cannabinoid receptor activation correlates with the pro-apoptotic action of the β2-adrenergic agonist, (R,R')-4-methoxy-1-naphthylfenoterol, in HepG2 hepatocarcinoma cells. (full – 2012) http/jpet.aspetjournals.org/content/early/2012/07/09/jpet.112.195206.long
    Anti-proliferative effects of anandamide in human hepatocellular carcinoma cells. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3439105/
    Serum Metabolic Profiling Study of Hepatocellular Carcinoma Infected with Hepatitis B or Hepatitis C Virus by Using Liquid Chromatography-Mass Spectrometry. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22946841
    Evaluation of Anti-invasion Effect of Cannabinoids on Human Hepatocarcinoma Cells. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22978792
    Study: Cannabis Agonists Produce Anti-Cancer Effects In Human Liver Cancer Cells (news – 2012) http/norml.org/news/2012/10/11/study-cannabis-agonists-produce-anti-cancer-effectsin-human-liver-cancer-cells
    Anti-Cancer Effects In Human Liver Cancer Cells Produced By Cannabis Agonists (news – 2012) http/www.imarijuana.com/tag/cannabinoid-agonists
    Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3674350/
    (R,R’-4’-methoxy-1-naphthylfenoterol Inhibits GPR55 signaling and the modulation of motility in human cancer cells (abst – 2013) http/www.abstractsonline.com/Plan/ViewAbstract.aspx?sKey=25370896-7d13-4f15-be76-f664d79b577d&cKey=87b7fec1-45cc-42b7-aca7-48c6b1d42773&mKey=9b2d28e7-24a0-466f-a3c9-07c21f6e9bc9
    PPARγ mediates the effects of WIN55,212-2, an synthetic cannabinoid, on the proliferation and apoptosis of the BEL-7402 hepatocarcinoma cells. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24062073
    (R,R')-4'-Methoxy-1-naphthylfenoterol Targets GPR55-mediated Ligand Internalization and Impairs Cancer Cell Motility. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24355564
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