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  • OBESITY*+ (2012-2013)

    To Be or Not To Be—Obese (full – 2012) http/endo.endojournals.org/content/152/10/3592.long
    The L-α-lysophosphatidylinositol/GPR55 system and its potential role in human obesity. (full – 2012) http/diabetes.diabetesjournals.org/content/61/2/281.long
    Resistance to diet-induced adiposity in cannabinoid receptor-1 deficient mice is not due to impaired adipocyte function. (full – 2012) http/www.nutritionandmetabolism.com/content/pdf/1743-7075-8-93.pdf
    Fatty acid amide hydrolase ablation promotes ectopic lipid storage and insulin resistance due to centrally mediated hypothyroidism. (full - 2012) http/www.pnas.org/content/109/37/14966.long
    Homology modelling of CB1 receptor and selection of potential inhibitor against Obesity. (full – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22829723?dopt=Abstract
    Cannabinoid Receptor 1 (CNR1) 4895 C/T Genetic Polymorphism was Associated with Obesity in Japanese Men. (full – 2012) https/www.jstage.jst.go.jp/article/jat/19/8/19_12732/_pdf
    Relationships between glucose, energy intake and dietary composition in obese adults with type 2 diabetes receiving the cannabinoid 1 (CB1) receptor antagonist, rimonabant (full – 2012) http/www.nutritionj.com/content/11/1/50
    Excess of the endocannabinoid anandamide during lactation induces overweight, fat accumulation and insulin resistance in adult mice (full – 2012) http/www.dmsjournal.com/content/4/1/35
    Hypothalamic 2-arachidonoylglycerol regulates multistage process of high-fat diet preferences. (full – 2012) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038609
    Dietary linoleic acid elevates endogenous 2-AG and anandamide and induces obesity. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3458187/
    Over-Expression of Monoacylglycerol Lipase (MGL) in Small Intestine Alters Endocannabinoid Levels and Whole Body Energy Balance, Resulting in Obesity. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3429419/
    Type 2 Diabetes Associated Changes in the Plasma Non-Esterified Fatty Acids, Oxylipins and Endocannabinoids (full – 2012) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0048852
    Endocannabinoids measurement in human saliva as potential biomarker of obesity. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3409167/?toolubmed
    Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
    The dynamic nature of type 1 cannabinoid receptor (CB1) gene transcription (full - 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02175.x/full
    Gut microbiota and the development of obesity. (full – 2012) http/scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112012000500007&lng=en&nrm=iso&tlng=en
    2-Arachidonoylglycerol Signaling in Forebrain Regulates Systemic Energy Metabolism (full – 2012) http/ac.els-cdn.com/S1550413112000526/1-s2.0-S1550413112000526-main.pdf?_tid=186a88ec-7369-11e3-8095-00000aab0f02&acdnat=1388638277_735058a6f79f41a9199132aed604fdab
    CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3342253/
    Hypothalamic CB1 Cannabinoid Receptors Regulate Energy Balance in Mice (full – 2012) http/press.endocrine.org/doi/full/10.1210/en.2012-1405
    Dietary linoleic acid elevates endogenous 2-arachidonoylglycerol and anandamide in Atlantic salmon (Salmo salar L.) and mice, and induces weight gain and inflammation in mice. (full - 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3548985/
    Hedonic eating is associated with increased peripheral levels of ghrelin and the endocannabinoid 2-arachidonoyl-glycerol in healthy humans: a pilot study. (full – 2012) http/press.endocrine.org/doi/full/10.1210/jc.2011-3018
    Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE) (full – 2012) http/fampra.oxfordjournals.org/content/29/5/521.full
    Cannabinoid Type 1 Receptor Gene Polymorphism and Macronutrient Intake. (full – 2012) http/www.karger.com/Article/FullText/343563
    The thrifty lipids: endocannabinoids and the neural control of energy conservation. (full – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22622030
    Dietary conditions and highly palatable food access alter rat cannabinoid receptor expression and binding density. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3621143/
    The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/21981246
    Cannabinoid signalling regulates inflammation and energy balance: The importance of the brain-gut axis. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22269477
    Diet-dependent modulation of hippocampal expression of endocannabinoid signalingrelated proteins in cannabinoid antagonist-treated obese rats. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23033907
    Cannabis exposure associated with weight reduction and β-cell protection in an obese rat model. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22421529
    Anti-obesity effects of the combined administration of CB1 receptor antagonist rimonabant and melanin-concentrating hormone antagonist SNAP-94847 in diet-inudced obese mice. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22473329
    Overexpression of cannabinoid CB2 receptor in the brain induces hyperglycaemia and a lean phenotype in adult mice. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22487302
    Cannabinol and cannabidiol exert opposing effects on rat feeding patterns. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22543671
    Stimulation of acumbens shell cannabinoid CB(1) receptors by noladin ether, a putative endocannabinoid, modulates food intake and dietary selection in rats. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22728691
    Associations of variants of CNR1 with obesity and obesity-related traits in Chinese women. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22244745
    Photoperiodic Changes in Endocannabinoid Levels and Energetic Responses to Altered Signalling at CB1 Receptors in Siberian Hamsters (abst – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2826.2012.02312.x/abstract
    The role of the endocannabinoid system in eating disorders: pharmacological implications. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22785439
    The potential use of cannabidiol in the therapy of metabolic syndrome (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22430005
    GPR119 as a fat sensor. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22560300 Role of G1359A polymorphism of the cannabinoid receptor gene on weight loss and adipocytokines levels after two different hypocaloric diets. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/21543209
    Simultaneous postprandial deregulation of the orexigenic endocannabinoid anandamide and the anorexigenic peptide YY in obesity (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/21844878
    The role of the endocannabinoid system in skeletal muscle and metabolic adaptations to exercise: potential implications for the treatment of obesity. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22943701
    Childhood Obesity and the Role of Dopamine D2 Receptor and Cannabinoid Receptor-1 Gene Polymorphisms. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23057570
    New vistas for treatment of obesity and diabetes? Endocannabinoid signalling and metabolism in the modulation of energy balance. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22674489
    Fatty acid flux and oxidation are increased by rimonabant in obese women. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22445512
    'Cannabis' receptor discovery may help understanding of obesity and pain (news – 2012) http/phys.org/news/2012-08-cannabis-receptor-discovery-obesity-pain.html
    How marijuana could help cure obesity-related diseases (news – 2012) http/news.yahoo.com/marijuana-could-help-cure-obesity-related-diseases-175900182.html
    Cannabis can help treat obesity (news – 2012) http/in.news.yahoo.com/cannabis-help-treat-obesity-121931025.html
    Marijuana Slims? Why Pot Smokers Are Less Obese (news – 2012) http/healthland.time.com/2011/09/08/marijuana-slims-pot-smoking-linked-to-lower-bodyweight/#ixzz21IEZq1Lg
    Fight obesity... with marijuana? (news – 2012) http/theweek.com/article/index/218940/fight-obesity-with-marijuana
    New Drug Could Help Maintain Long-Term Weight Loss (news – 2012) http/www.sciencedaily.com/releases/2012/07/120726122116.htm

    Dietary Linoleic Acid Elevates the Endocannabinoids 2-AG and Anandamide and Promotes Weight Gain in Mice Fed a Low Fat Diet (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3889814/
    The impact of marijuana use on glucose, insulin, and insulin resistance among US adults (full – 2013) http/www.amjmed.com/article/S0002-9343%2813%2900200-3/fulltext
    The cannabinoid Δ(9)-tetrahydrocannabivarin (THCV) ameliorates insulin sensitivity in two mouse models of obesity. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3671751/
    Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats. (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063449
    Chronic treatment with krill powder reduces plasma triglyceride and anandamide levels in mildly obese men (full – 2013) http/www.lipidworld.com/content/12/1/78
    Alterations to Melanocortinergic, GABAergic and Cannabinoid Neurotransmission Associated with Olanzapine-Induced Weight Gain (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0033548
    Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons (full – 2013) http/www.pnas.org/content/110/24/E2229.full
    Food for thought: hormonal, experiential, and neural influences on feeding and obesity. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3818543/
    Hypothalamic 2-Arachidonoylglycerol Regulates Multistage Process of High-Fat Diet Preferences (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0038609
    Moderation of antipsychotic-induced weight gain by energy balance gene variants in the RUPP autism network risperidone studies (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3693401/
    Orexin neurons use endocannabinoids to break obesity-induced inhibition (full – 2013) http/www.pnas.org/content/110/24/9625.full
    Effect of high fat-diet and obesity on gastrointestinal motility. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3890396/
    Insulin induces long-term depression of VTA dopamine neurons via endocannabinoids (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC4072656/
    Cannabinoids, eating behaviour, and energy homeostasis. (full – 2013) http/onlinelibrary.wiley.com/doi/10.1002/dta.1594/full
    Reduced Food Intake is the Major Contributor to the Protective Effect of Rimonabant on Islet in Established Obesity-Associated Type 2 Diabetes. (full – 2013) http/www.eymj.org/DOIx.php?id=10.3349/ymj.2013.54.5.1127
    Developmental Role for Endocannabinoid Signaling in Regulating Glucose Metabolism and Growth. (full – 2013) http/diabetes.diabetesjournals.org/content/62/7/2359.full?sid=2f5bda2b-a9c7-432a-9588-80c99189164d
    Monounsaturated fatty acids generated via stearoyl CoA desaturase-1 are endogenous inhibitors of fatty acid amide hydrolase. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3839776/
    Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines (full – 2013) http/eurheartj.oxfordjournals.org/content/34/27/2063.long
    Fatty Acid Modulation of the Endocannabinoid System and the Effect on Food Intake and Metabolism (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3677644/
    Effect of Nelumbo nucifera Petal Extracts on Lipase, Adipogenesis, Adipolysis, and Central Receptors of Obesity (full – 2013) http/www.hindawi.com/journals/ecam/2013/145925/
    The serine hydrolase ABHD6 Is a critical regulator of the metabolic syndrome. (full – 2013) http/www.cell.com/cell-reports/fulltext/S2211-1247%2813%2900507-X
    A potential role for GPR55 in gastrointestinal functions. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3660623/
    Genetic variation in the cannabinoid receptor gene (CNR1) (G1359A polymorphism) and their influence on anthropometric parameters and metabolic parameters under a high monounsaturated vs. high polyunsaturated fat hypocaloric diets. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23337343
    Cannabis and Δ(9)-tetrahydrocannabinol (THC) for weight loss? (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23410498
    Endocannabinoids and obesity. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23374723
    Novel antiobesity agents: Synthesis and pharmacological evaluation of analogues of Rimonabant and of LH21. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23434135
    Fat to treat fat: Emerging relationship between dietary PUFA, endocannabinoids, and obesity. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23466458
    The endocannabinoid system in obesity (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23596738
    Effects of CB1 receptor blockade on monosodium glutamate induced hypometabolic and hypothalamic obesity in rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23620336
    Activation of type 2 cannabinoid receptors (CB2R) promotes fatty acid oxidation through the SIRT1/PGC-1α pathway. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23747418
    Polymorphism rs3123554 in CNR2 reveals gender-specific effects on body weight and affects loss of body weight and cerebral insulin action. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23839870
    Analysis of the "endocannabinoidome" in peripheral tissues of obese Zucker rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23830028
    The Role of the Endocannabinoid System in Eating Disorders: Neurochemical and Behavioural Preclinical Evidence. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23829365
    Novel effects of the cannabinoid inverse agonist AM 251 on parameters related to metabolic syndrome in obese Zucker rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23932644
    Endocannabinoid crosstalk between placenta and maternal fat in a baboon model (Papio spp.) of obesity. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24008071
    High fat diet and body weight have different effects on cannabinoid CB1 receptor expression in rat nodose ganglia. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24145047
    Long-term supplementation of honokiol and magnolol ameliorates body fat accumulation, insulin resistance, and adipose inflammation in high-fat fed mice. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23901038
    Role of Genetic Variation in the Cannabinoid Receptor Gene (CNR1) (G1359A Polymorphism) on Weight Loss and Cardiovascular Risk Factors After Liraglutide Treatment in Obese Patients With Diabetes Mellitus Type 2. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24322329
    Regulation of GPR55 in rat white adipose tissue and serum LPI by nutritional status, gestation, gender and pituitary factors. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24378736
    The regulation of food intake by the gut-brain axis: implications for obesity (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/22710925
    Concurrent pharmacological modification of cannabinoid-1 and glucagon-like peptide-1 receptor activity affects feeding behavior and body weight in rats fed a free-choice, highcarbohydrate diet. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24370558
    Effects of C358A polymorphism of the endocannabinoid degrading enzyme fatty acid amide hydrolase (FAAH) on weight loss, adipocytokines levels, and insulin resistance after a high polyunsaturated fat diet in obese patients. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24445122
    Key Shift in Brain That Creates Drive to Overeat Identified (news – 2013) http/www.sciencedaily.com/releases/2013/04/130429154214.htm
    Regular Marijuana Use is Associated With Favorable Indices to Diabetic Control, Say Investigators (news – 2013) http/www.news-medical.net/news/20130515/Regular-marijuana-use-is-associated-with-favorableindices-related-to-diabetic-control-say-investigators.aspx
    Marijuana Users Have Better Blood Sugar Control (news – 2013) http/www.sciencedaily.com/releases/2013/05/130515085208.htm
    Study: Why Pot Smokers Are Skinnier (news – 2013) http/www.theatlantic.com/health/archive/2013/05/study-why-pot-smokers-are-skinnier/275846/
    Cannabis linked to prevention of diabetes (news – 2013) http/www.independent.co.uk/life-style/health-and-families/health-news/cannabis-linked-to-prevention-ofdiabetes-8616314.html
    Study: Marijuana Smokers Are Thinner And Healthier Than Non-Users (news – 2013) http/www.opposingviews.com/i/society/study-marijuana-smokers-are-thinner-and-healthier-non-users
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