Potential role for CB2 selective ligands as immunosuppressive agents (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/arti...tool=pmcentrez
Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence (full - 2007) http://jpet.aspetjournals.org/content/322/3/1144.long
Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision (full – 2007) http://journals.lww.com/anesthesiolo...vation.21.aspx
In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full - 2008) http://www.pubmedcentral.nih.gov/art...tool=pmcentrezEffects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000) http://www.ncbi.nlm.nih.gov/pmc/arti...tool=pmcentrez
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full – 2002) http://bloodjournal.hematologylibrar...a7d081bcc2771d
Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15556131
CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility (full - 2005) http://www.iovs.org/content/46/6/1988.long
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (link to PDF– 2005) http://www.springerlink.com/content/.../fulltext.html
Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3K-dependent mechanisms: role of NF-kappaB and p53 (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/17017986
Chemical modification of the naphthoyl 3-position of JWH-015: In search of a fluorescent probe to the cannabinoid CB2 receptor (abst – 2005) http://www.sciencedirect.com/science...60894X05006803
CB2 cannabinoid receptor agonist, JWH-015 triggers apoptosis in immune cells: Potential role for CB2 selective ligands as immunosuppressive agents (full – 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864948/
CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways (full – 2008) http://ajpheart.physiology.org/content/294/3/H1145.long
Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling (full – 2008) http://www.fasebj.org/content/22/10/3685.long
Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18991890
Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2 (full - 2009) http://www.nature.com/bjc/journal/v1.../6605248a.html
The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/1...&ordinalpos=18
Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20514518
Now, There's a Test for That -- Norchem's "Fake Marijuana" Test Reveals Significantly Increased Abuse of Spice/K2 (news – 2010) http://www.marketwire.com/press-rele...se-1356247.htm
Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...4/?tool=pubmed
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...1/?tool=pubmed
The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
Beyond THC: The New Generation of Cannabinoid Designer Drugs (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...7/?tool=pubmed
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro (full – 2011) http://onlinelibrary.wiley.com/doi/1...1.01519.x/full
Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyl-d-Aspartic Acid (full – 2011) http://journals.lww.com/anesthesia-a...noid_2.33.aspx
Latest blood test detects 12 popular synthetic cannabinoids in "fake pot" (news – 2011) http://www.thefreelibrary.com/Latest.....-a0261876557
Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news – 2011) http://www.justice.g`ov/dea/pubs/pressrel/pr030111.html
Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats (full – 2012) http://onlinelibrary.wiley.com/doi/1...hep.25625/full
Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists (full – 2012) http://onlinelibrary.wiley.com/doi/1...jbmr.1732/full
GPR18 in microglia: implications for the CNS and endocannabinoid system signaling (full – 2012) http://onlinelibrary.wiley.com/doi/1...2.02019.x/full
Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548934/
Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936256/
The CB(2)-preferring agonist JWH015 also potently and efficaciously activates CB(1) in autaptic hippocampal neurons (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601544/
Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683
Cannabinoids and muscular pain. Effectiveness of the local administration in rat (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22354705
Acute toxicity due to the confirmed consumption of synthetic cannabinoids: Clinical and laboratory findings (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22971158
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells (full – 2013) http://jpet.aspetjournals.org/conten...13.205120.long
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674350/
Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function (full – 2013) http://www.clinsci.org/cs/124/0467/1240467.pdf
Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23706402
Cannabinoid Effects on β Amyloid Fibril and Aggregate Formation, Neuronal and Microglial-Activated Neurotoxicity In Vitro (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24030360
Vascular targets for cannabinoids: animal and human studies (full – 2014) http://onlinelibrary.wiley.com/doi/1...bph.12560/full
Cannabinoids as therapeutic agents in cancer: current status and future implications (link to PDF- 2014) http://www.impactjournals.com/oncota...e&op=view&path[]=2233
Evaluation of selective cannabinoid CB1 and CB2 receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24561047
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24259678
Intrathecal Injection of JWH015 Attenuates Remifentanil-Induced Postoperative Hyperalgesia by Inhibiting Activation of Spinal Glia in a Rat Model (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24651239
Opposing control of cannabinoid receptor stimulation on amyloid-beta-induced reactive gliosis: in vitro and in vivo evidence (full - 2007) http://jpet.aspetjournals.org/content/322/3/1144.long
Spinal cannabinoid receptor type 2 activation reduces hypersensitivity and spinal cord glial activation after paw incision (full – 2007) http://journals.lww.com/anesthesiolo...vation.21.aspx
In vivo effects of CB2 receptor-selective cannabinoids on the vasculature of normal and arthritic rat knee joints (full - 2008) http://www.pubmedcentral.nih.gov/art...tool=pmcentrezEffects of cannabinoid receptor agonists on neuronally-evoked contractions of urinary bladder tissues isolated from rat, mouse, pig, dog, monkey and human (full - 2000) http://www.ncbi.nlm.nih.gov/pmc/arti...tool=pmcentrez
Targeting CB2 cannabinoid receptors as a novel therapy to treat malignant lymphoblastic disease (full – 2002) http://bloodjournal.hematologylibrar...a7d081bcc2771d
Species comparison and pharmacological characterization of rat and human CB2 cannabinoid receptors (abst - 2004) http://www.ncbi.nlm.nih.gov/pubmed/15556131
CB2 cannabinoid receptors in trabecular meshwork cells mediate JWH015-induced enhancement of aqueous humor outflow facility (full - 2005) http://www.iovs.org/content/46/6/1988.long
Stimulation of cannabinoid receptor 2 (CB2) suppresses microglial activation (link to PDF– 2005) http://www.springerlink.com/content/.../fulltext.html
Avoidance of Abeta[(25-35)] / (H(2)O(2)) -induced apoptosis in lymphocytes by the cannabinoid agonists CP55,940 and JWH-015 via receptor-independent and PI3K-dependent mechanisms: role of NF-kappaB and p53 (abst – 2005) http://www.ncbi.nlm.nih.gov/pubmed/17017986
Chemical modification of the naphthoyl 3-position of JWH-015: In search of a fluorescent probe to the cannabinoid CB2 receptor (abst – 2005) http://www.sciencedirect.com/science...60894X05006803
CB2 cannabinoid receptor agonist, JWH-015 triggers apoptosis in immune cells: Potential role for CB2 selective ligands as immunosuppressive agents (full – 2006) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1864948/
CB2 cannabinoid receptor agonist JWH-015 modulates human monocyte migration through defined intracellular signaling pathways (full – 2008) http://ajpheart.physiology.org/content/294/3/H1145.long
Endocannabinoids enhance lipid synthesis and apoptosis of human sebocytes via cannabinoid receptor-2-mediated signaling (full – 2008) http://www.fasebj.org/content/22/10/3685.long
Behavioral effects of CB2 cannabinoid receptor activation and its influence on food and alcohol consumption (abst - 2008) http://www.ncbi.nlm.nih.gov/pubmed/18991890
Presence and regulation of cannabinoid receptors in human retinal pigment epithelial cells (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
Inhibition of human tumour prostate PC-3 cell growth by cannabinoids R(+)-Methanandamide and JWH-015: Involvement of CB2 (full - 2009) http://www.nature.com/bjc/journal/v1.../6605248a.html
The activation of cannabinoid CB2 receptors stimulates in situ and in vitro beta-amyloid removal by human macrophages (abst – 2009) http://www.ncbi.nlm.nih.gov/pubmed/1...&ordinalpos=18
Protective effects of the synthetic cannabinoids CP55,940 and JWH-015 on rat brain mitochondria upon paraquat exposure (abst – 2010) http://www.ncbi.nlm.nih.gov/pubmed/20514518
Now, There's a Test for That -- Norchem's "Fake Marijuana" Test Reveals Significantly Increased Abuse of Spice/K2 (news – 2010) http://www.marketwire.com/press-rele...se-1356247.htm
Crosstalk between Chemokine Receptor CXCR4 and Cannabinoid Receptor CB(2) in Modulating Breast Cancer Growth and Invasion (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...4/?tool=pubmed
Marijuana-based Drugs: Innovative Therapeutics or Designer Drugs of Abuse? (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...1/?tool=pubmed
The Antinociceptive Effects of JWH-015 in Chronic Inflammatory Pain Are Produced by Nitric Oxide-cGMP-PKG-KATP Pathway Activation Mediated by Opioids (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
Beyond THC: The New Generation of Cannabinoid Designer Drugs (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...7/?tool=pubmed
Cannabinoids and bone: endocannabinoids modulate human osteoclast function in vitro (full – 2011) http://onlinelibrary.wiley.com/doi/1...1.01519.x/full
Intrathecal Administration of the Cannabinoid 2 Receptor Agonist JWH015 Can Attenuate Cancer Pain and Decrease mRNA Expression of the 2B Subunit of N-Methyl-d-Aspartic Acid (full – 2011) http://journals.lww.com/anesthesia-a...noid_2.33.aspx
Latest blood test detects 12 popular synthetic cannabinoids in "fake pot" (news – 2011) http://www.thefreelibrary.com/Latest.....-a0261876557
Chemicals Used in "Spice" and "K2" Type Products Now Under Federal Control and Regulation (news – 2011) http://www.justice.g`ov/dea/pubs/pressrel/pr030111.html
Cannabinoid receptor 2 agonist ameliorates mesenteric angiogenesis and portosystemic collaterals in cirrhotic rats (full – 2012) http://onlinelibrary.wiley.com/doi/1...hep.25625/full
Disease modification of breast cancer-induced bone remodeling by cannabinoid 2 receptor agonists (full – 2012) http://onlinelibrary.wiley.com/doi/1...jbmr.1732/full
GPR18 in microglia: implications for the CNS and endocannabinoid system signaling (full – 2012) http://onlinelibrary.wiley.com/doi/1...2.02019.x/full
Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3548934/
Spice drugs are more than harmless herbal blends: A review of the pharmacology and toxicology of synthetic cannabinoids (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3936256/
The CB(2)-preferring agonist JWH015 also potently and efficaciously activates CB(1) in autaptic hippocampal neurons (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3601544/
Contrasting protective effects of cannabinoids against oxidative stress and amyloid-β evoked neurotoxicity in vitro (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22233683
Cannabinoids and muscular pain. Effectiveness of the local administration in rat (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22354705
Acute toxicity due to the confirmed consumption of synthetic cannabinoids: Clinical and laboratory findings (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22971158
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells (full – 2013) http://jpet.aspetjournals.org/conten...13.205120.long
Involvement of PPARγ in the antitumoral action of cannabinoids on hepatocellular carcinoma (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3674350/
Chronic activation of cannabinoid receptors in vitro does not compromise mouse islet function (full – 2013) http://www.clinsci.org/cs/124/0467/1240467.pdf
Cannabinoid CB2 receptor activation attenuates cytokine-evoked mucosal damage in a human colonic explant model without changing epithelial permeability (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23706402
Cannabinoid Effects on β Amyloid Fibril and Aggregate Formation, Neuronal and Microglial-Activated Neurotoxicity In Vitro (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24030360
Vascular targets for cannabinoids: animal and human studies (full – 2014) http://onlinelibrary.wiley.com/doi/1...bph.12560/full
Cannabinoids as therapeutic agents in cancer: current status and future implications (link to PDF- 2014) http://www.impactjournals.com/oncota...e&op=view&path[]=2233
Evaluation of selective cannabinoid CB1 and CB2 receptor agonists in a mouse model of lipopolysaccharide-induced interstitial cystitis (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24561047
Combined antiproliferative effects of the aminoalkylindole WIN55,212-2 and radiation in breast cancer cells (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24259678
Intrathecal Injection of JWH015 Attenuates Remifentanil-Induced Postoperative Hyperalgesia by Inhibiting Activation of Spinal Glia in a Rat Model (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24651239