Selective blockade of 2-arachidonoylglycerol hydrolysis produces cannabinoid behavioral effects (full – 2009)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2605181/
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling (full – 2009)http://jpet.aspetjournals.org/content/331/2/591.long
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784730/
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ (full – 2011)http://onlinelibrary.wiley.com/doi/1...1.01444.x/full
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum (full – 2011)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224879/
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation (full – 2011)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249428/
Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hemorrhages in mice (full – 2011)http://jpet.aspetjournals.org/conten...10.175778.long
Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat (full – 2012) http://onlinelibrary.wiley.com/doi/1...2.02179.x/full
Monoacylglycerol lipase is a new therapeutic target for Alzheimer’s disease (full – 2012)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513645/
Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine inflammatory pain model (abst – 2013)http://www.ncbi.nlm.nih.gov/pubmed/24384256
Study: Cannabinoids Offer Treatment For Severe Lung Disease (news – 2013) http://www.leafscience.com/2013/11/2...-lung-disease/
Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice (full – 2013)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808422/
Dynamic changes to the endocannabinoid system in models of chronic pain (full – 2012)http://rstb.royalsocietypublishing.o...f-857201f5e069
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model (full – 2013)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717616/
Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Anti-Withdrawal Effects in Morphine-Dependent Mice (full – 2013)http://www.ncbi.nlm.nih.gov/pubmed/23303065
Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657109/
Peripheral and Spinal Activation of Cannabinoid Receptors by Joint Mobilization Alleviates Postoperative Pain in Mice (abst – 2013)http://www.ncbi.nlm.nih.gov/pubmed/24120553
The endocannabinoid system mediates aerobic exercise-induced antinociception in rats (abst – 2013)http://www.ncbi.nlm.nih.gov/pubmed/24148812
Experimental cannabinoid 2 receptor-mediated immune modulation in sepsis (full – 2014) http://www.hindawi.com/journals/mi/2014/978678/
The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109781/
Prolonged monoacylglycerol lipase blockade causes equivalent CB1-receptor mediated adaptations in FAAH wild type and knockout mice (full – 2014) http://jpet.aspetjournals.org/conten...14.212753.long
Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/24476943
Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24709540
Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/24703998
Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/24858366
Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24906199
The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184 (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24911644
Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24915981
The monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24973119
Endocannabinoid modulation by FAAH and MAGL within the analgesic circuitry of the periaqueductal grey (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/25041240
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling (full – 2009)http://jpet.aspetjournals.org/content/331/2/591.long
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarization-induced suppression of excitation in autaptic hippocampal neurons (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784730/
Inhibition of COX-2 expression by endocannabinoid 2-arachidonoylglycerol is mediated via PPAR-γ (full – 2011)http://onlinelibrary.wiley.com/doi/1...1.01444.x/full
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum (full – 2011)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224879/
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation (full – 2011)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249428/
Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hemorrhages in mice (full – 2011)http://jpet.aspetjournals.org/conten...10.175778.long
Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat (full – 2012) http://onlinelibrary.wiley.com/doi/1...2.02179.x/full
Monoacylglycerol lipase is a new therapeutic target for Alzheimer’s disease (full – 2012)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513645/
Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine inflammatory pain model (abst – 2013)http://www.ncbi.nlm.nih.gov/pubmed/24384256
Study: Cannabinoids Offer Treatment For Severe Lung Disease (news – 2013) http://www.leafscience.com/2013/11/2...-lung-disease/
Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice (full – 2013)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808422/
Dynamic changes to the endocannabinoid system in models of chronic pain (full – 2012)http://rstb.royalsocietypublishing.o...f-857201f5e069
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model (full – 2013)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717616/
Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Anti-Withdrawal Effects in Morphine-Dependent Mice (full – 2013)http://www.ncbi.nlm.nih.gov/pubmed/23303065
Repeated Low Dose Administration of the Monoacylglycerol Lipase Inhibitor JZL184 Retains CB1 Receptor Mediated Antinociceptive and Gastroprotective Effects (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3657109/
Peripheral and Spinal Activation of Cannabinoid Receptors by Joint Mobilization Alleviates Postoperative Pain in Mice (abst – 2013)http://www.ncbi.nlm.nih.gov/pubmed/24120553
The endocannabinoid system mediates aerobic exercise-induced antinociception in rats (abst – 2013)http://www.ncbi.nlm.nih.gov/pubmed/24148812
Experimental cannabinoid 2 receptor-mediated immune modulation in sepsis (full – 2014) http://www.hindawi.com/journals/mi/2014/978678/
The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109781/
Prolonged monoacylglycerol lipase blockade causes equivalent CB1-receptor mediated adaptations in FAAH wild type and knockout mice (full – 2014) http://jpet.aspetjournals.org/conten...14.212753.long
Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/24476943
Prior stimulation of the endocannabinoid system prevents methamphetamine-induced dopaminergic neurotoxicity in the striatum through activation of CB2 receptors (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24709540
Hemopressin, an inverse agonist of cannabinoid receptors, inhibits neuropathic pain in rats (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/24703998
Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/24858366
Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24906199
The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184 (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24911644
Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24915981
The monoacylglycerol lipase inhibitor JZL184 is neuroprotective and alters glial cell phenotype in the chronic MPTP mouse model (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24973119
Endocannabinoid modulation by FAAH and MAGL within the analgesic circuitry of the periaqueductal grey (abst – 2014)http://www.ncbi.nlm.nih.gov/pubmed/25041240