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S-444823
Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22421019
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4(PM49)
Synthetic cannabinoid quinones: Preparation, in-vitro antiproliferative effects and in-vivo prostate antitumor activity (abst – 2013)http://www.sci...
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RIMONABANT / ACOMPLIA / SR141716 / SR1
Getting high on the endocannabinoid system (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3997295/
Involvement of the Cannabinoid CB1 Receptor in Modulation of Dopamine Output in the Prefrontal Cortex Associated with Food Restriction in Rats (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954872/
Vascular targets for cannabinoids: animal and human studies (full – 2014) http://onlinelibrary.wiley.com/doi/1...bph.12560/full
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective (full– 2014)http://www.ncbi.nlm.n...
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R(+)-METHANANANDAMIDE / AM-356
(R)-methanandamide: a chiral novel anandamide possessing higher potency and metabolic stability (abst – 1994)http://www.ncbi.nlm.nih.gov/pubmed/8021930
Cannabinoids might reduce spasticity in multiple sclerosis (full – 2000) http://www.ncbi.nlm.nih.gov/pmc/arti...tool=pmcentrez
Protective effects of cannabinoid receptor ligands analogous to anandamide against cocaine toxicity (abst – 2001)http://www.ncbi.nlm.nih.gov/pubmed/11828716
Endogenous cannabinoids improve myocardial resistance to arrhythmogenic effects of coronary occlusion and reperfusion: a possible mechanism (abst – 2002) http://www....
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PB-22 /QUPIC / 'CRAZY MONKEY'
'Crazy Monkey' Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid (full – 2014)http://informahealthcare.com...
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PF-3845
Discovery and characterization of a highly selective FAAH inhibitor that reduces inflammatory pain (full – 2009)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692831/ Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hem...
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OMDM-2
Novel selective and metabolically stable inhibitors of anandamide cellular uptake (abst – 2003) http://www.ncbi.nlm.nih.gov/pubmed/12732359
In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake (abst – 2004)http://w...
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ORG-27569
Parameterization of Org27569: An allosteric modulator of the cannabinoid CB(1) G protein-coupled receptor (full – 2011)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3145811/ Allosteric modulator ORG27569 induces CB1...
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DAGL / DIACYLGLYCEROL LIPASE > 2008-2014
Presence of functional cannabinoid receptors in human endocrine pancreas. (abst – 2008) http://www.frontiersin.org/publications/18092149 Autocrine Endocannabinoid Signaling through CB1 Receptors Poten...
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CBR - GPR158 / CANNABINOID RECEPTOR > 2009-2013
The presence of aberrant DNA methylation in noncancerous esophageal mucosae in association with smoking history: a target for risk diagnosis and prevention of esophageal cancers....
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OMDM-1
Up-regulation of the endocannabinoid system in the uterus of leptin knockout (ob/ob) mice and implications for fertility (full – 2005)http://molehr...
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CBR - GPR119 / CANNABINOID RECEPTOR > 2007-2014
A role for beta-cell-expressed G protein-coupled receptor 119 in glycemic control by enhancing glucose-dependent insulin release. (full – 2007) http://endo.endojournals.org/content/148/6/2601.long Endogenous and synthetic agonists of GPR119 differ in signalling pathways and their...
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O-1918
Selective ligands and cellular effectors of a G protein-coupled endothelial cannabinoid receptor (full – 2003)http://molpharm.aspetjournals.org/content/63/3/699.long Heterogeneity in the mechanisms of vasorelaxation to anandamide in resistan...
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O-1966
CB2 receptor activation attenuates microcirculatory dysfunction during cerebral ischemic/reperfusion injury (full - 2009)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3319431/ Modulation of inflammatory responses by a cannabinoid...
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O-2050
Suppression of feeding, drinking, and locomotion by a putative cannabinoid receptor ‘silent antagonist (abst – 2005)http://www.sciencedirect.com/science...14299905012197 Hypothalamic 2-arachidon...
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