Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment (full – 2010) http://www.fasebj.org/content/24/3/788.long
The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia (full - 2010) http://stroke.ahajournals.org/content/41/12/2956.long
Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke (link to PDF – 2010) http://www.mdpi.com/1424-8247/3/7/2197
The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic ischemic brain damage in mice is mediated by CB(2) and adenosine receptors (abst – 2010) http://www.unboundmedicine.com/medli...ine_receptors_
Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst – 2011) http://www.unboundmedicine.com/medli...fusion_Injury_
Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21443454
Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia ischemia in newborn pigs (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550
Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21145311
Medical cannabis: the opportunity versus the temptation (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22352284
Contribution of Hypothermia and CB(1) Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model (full– 2012) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
Update on the role of cannabinoid receptors after ischemic stroke (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/arti...5/?tool=pubmed
Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection (full – 2012) http://stroke.ahajournals.org/content/43/1/211.long
Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446851/
Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies (full – 2012) http://onlinelibrary.wiley.com/doi/1...12.02042.x/pdf
Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion (full – 2012) http://www.jneuroinflammation.com/content/9/1/76
Cerebroprotective effects of TAK-937, a cannabinoid receptor agonist, on ischemic brain damage in middle cerebral artery occluded rats and non-human primates (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22119394
The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21909954
Effects of cannabinoid receptor agonist WIN 55,212-2 on blood-brain barrier disruption in focal cerebral ischemia in rats (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22678129
The Role of Cannabinoids In Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22420307
Orally administered oleoylethanolamide protects mice from focal cerebral ischemic injury by activating peroxisome proliferator-activated receptor α (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22480617
Cannabinoid Receptor Subtypes 1 and 2 Mediate Long-Lasting Neuroprotection and Improve Motor Behaviour Deficits After Transient Focal Cerebral Ischemia (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23069763
WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23202804
WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23202804
“A Marijuana Bud a Day Keeps the Stroke Away" (news – 2012) http://www.tokeofthetown.com/2012/04...troke_away.php
Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia (full – 2013) http://onlinelibrary.wiley.com/doi/1...jnc.12347/full
Is the cardiovascular system a therapeutic target for cannabidiol? (full – 2013) http://onlinelibrary.wiley.com/doi/1...2.04351.x/full
Drug-Induced Hypothermia in Stroke Models: Does it Always Protect? (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081530/
Does smoking marijuana cause stroke? (article – 2013) http://www.thepoisonreview.com/2013/...-cause-stroke/
WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23148948
Nicotine-Induced Neuroprotection Against Ischemic Injury Involves Activation of Endocannabinoid System in Rats (abst – 2013) http://link.springer.com/article/10....064-012-0927-6
Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23880371
Activation of Cannabinoid CB2 Receptor-Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23414569
Acupuncture therapy for stroke patients (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24215922
Effect of cannabinoid CB2 receptor agonism on learning and memory in a mouse model of photothrombosis (abst – 2013) http://www.fasebj.org/cgi/content/me...4?sid=eea722c0 -971c-4daa-8b8c-38c0c63c19ad
Cerebroprotective effects of TAK-937, a novel cannabinoid receptor agonist, in permanent and thrombotic focal cerebral ischemia in rats: Therapeutic time window, combination with t-PA and efficacy in aged rats (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23791950
Therapeutic Potential of Cannabinoids in Neurodegenerative Disorders: A Selective Review (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23829360
Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/22371074
Synthetic Cannabis and Acute Ischemic Stroke (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24119618
Ischemic stroke after use of the synthetic marijuana "spice" (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24212384
Unique effects of compounds active at both cannabinoid and serotonin receptors during stroke (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24323810
Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury (news – 2013) http://www.sciencedaily.com/releases...0221141140.htm
Cannabinoid Trans-Caryophyllene Protects Brain Cells From Ischemia (news – 2013) http://www.medicalnewstoday.com/articles/256799.php
Smoking "spice" associated with stroke in healthy, young adults (news – 2013) http://www.medicalnewstoday.com/releases/269132.php
Cannabinoids: well-suited candidates for the treatment of perinatal brain injury (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061885/
Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases (link to PDF – 2014) http://www.mdpi.com/1420-3049/19/11/18781
The cannabinoid CB2 receptor agonist GW405833 does not ameliorate brain damage induced by hypoxia-ischemia in rats (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24721671
Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24874648
Severe rhabdomyolysis and intracranial hemorrhage associated with synthetic cannabinoid: a case report (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25179201
A case of acute cerebral ischemia following inhalation of a synthetic cannabinoid (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25241766
Mn-SOD Upregulation by Electroacupuncture Attenuates Ischemic Oxidative Damage via CB1R-Mediated STAT3 Phosphorylation (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25432886
Cannabinoids in experimental stroke: a systematic review and meta-analysis (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25492113
Protective effects of cannabidiol against hippocampal cell death and cognitive impairment induced by bilateral common carotid artery occlusion in mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24532152
Magnolol protects neurons against ischemia injury via the downregulation of p38/MAPK, CHOP and nitrotyrosine. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25038313
Glycogen synthase kinase-3β is involved in electroacupuncture pretreatment via the cannabinoid CB1 receptor in ischemic stroke (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/23943518
The cannabinoid WIN55212-2 promotes neural repair after neonatal hypoxia-ischemia (full - 2010) http://stroke.ahajournals.org/content/41/12/2956.long
Therapeutic Potential of Non-Psychotropic Cannabidiol in Ischemic Stroke (link to PDF – 2010) http://www.mdpi.com/1424-8247/3/7/2197
The Multiplicity of Action of Cannabinoids: Implications for Treating Neurodegeneration. (abst - 2010) http://www.ncbi.nlm.nih.gov/pubmed/20875047
The neuroprotective effect of cannabidiol in an in vitro model of newborn hypoxic ischemic brain damage in mice is mediated by CB(2) and adenosine receptors (abst – 2010) http://www.unboundmedicine.com/medli...ine_receptors_
Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst – 2011) http://www.unboundmedicine.com/medli...fusion_Injury_
Cannabinoid receptor type 2 activation yields delayed tolerance to focal cerebral ischemia (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21443454
Cannabidiol reduces brain damage and improves functional recovery after acute hypoxia ischemia in newborn pigs (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21654550
Residual effects of focal brain ischaemia upon cannabinoid CB(1) receptor density and functionality in female rats (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21145311
Medical cannabis: the opportunity versus the temptation (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/22352284
Contribution of Hypothermia and CB(1) Receptor Activation to Protective Effects of TAK-937, a Cannabinoid Receptor Agonist, in Rat Transient MCAO Model (full– 2012) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
Update on the role of cannabinoid receptors after ischemic stroke (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/arti...5/?tool=pubmed
Cannabinoid type 2 receptor activation downregulates stroke-induced classic and alternative brain macrophage/microglial activation concomitant to neuroprotection (full – 2012) http://stroke.ahajournals.org/content/43/1/211.long
Reduced infarct size and accumulation of microglia in rats treated with WIN 55,212-2 after neonatal stroke (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3446851/
Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies (full – 2012) http://onlinelibrary.wiley.com/doi/1...12.02042.x/pdf
Neuroprotection by inhibiting the c-Jun N-terminal kinase pathway after cerebral ischemia occurs independently of interleukin-6 and keratinocyte-derived chemokine (KC/CXCL1) secretion (full – 2012) http://www.jneuroinflammation.com/content/9/1/76
Cerebroprotective effects of TAK-937, a cannabinoid receptor agonist, on ischemic brain damage in middle cerebral artery occluded rats and non-human primates (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22119394
The Cannabinoid WIN 55212-2 Mitigates Apoptosis and Mitochondrial Dysfunction After Hypoxia Ischemia. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/21909954
Effects of cannabinoid receptor agonist WIN 55,212-2 on blood-brain barrier disruption in focal cerebral ischemia in rats (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22678129
The Role of Cannabinoids In Inflammatory Modulation of Allergic Respiratory Disorders, Inflammatory Pain and Ischemic Stroke (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22420307
Orally administered oleoylethanolamide protects mice from focal cerebral ischemic injury by activating peroxisome proliferator-activated receptor α (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22480617
Cannabinoid Receptor Subtypes 1 and 2 Mediate Long-Lasting Neuroprotection and Improve Motor Behaviour Deficits After Transient Focal Cerebral Ischemia (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23069763
WIN55,212-2 protects oligodendrocyte precursor cells in stroke penumbra following permanent focal cerebral ischemia in rats (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23202804
WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/23202804
“A Marijuana Bud a Day Keeps the Stroke Away" (news – 2012) http://www.tokeofthetown.com/2012/04...troke_away.php
Molecular targets underlying SUMO-mediated neuroprotection in brain ischemia (full – 2013) http://onlinelibrary.wiley.com/doi/1...jnc.12347/full
Is the cardiovascular system a therapeutic target for cannabidiol? (full – 2013) http://onlinelibrary.wiley.com/doi/1...2.04351.x/full
Drug-Induced Hypothermia in Stroke Models: Does it Always Protect? (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4081530/
Does smoking marijuana cause stroke? (article – 2013) http://www.thepoisonreview.com/2013/...-cause-stroke/
WIN55, 212-2 promotes differentiation of oligodendrocyte precursor cells and improve remyelination through regulation of the phosphorylation level of the ERK 1/2 via cannabinoid receptor 1 after stroke-induced demyelination (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23148948
Nicotine-Induced Neuroprotection Against Ischemic Injury Involves Activation of Endocannabinoid System in Rats (abst – 2013) http://link.springer.com/article/10....064-012-0927-6
Activation of STAT3 is involved in neuroprotection by electroacupuncture pretreatment via cannabinoid CB1 receptors in rats (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23880371
Activation of Cannabinoid CB2 Receptor-Mediated AMPK/CREB Pathway Reduces Cerebral Ischemic Injury. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23414569
Acupuncture therapy for stroke patients (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24215922
Effect of cannabinoid CB2 receptor agonism on learning and memory in a mouse model of photothrombosis (abst – 2013) http://www.fasebj.org/cgi/content/me...4?sid=eea722c0 -971c-4daa-8b8c-38c0c63c19ad
Cerebroprotective effects of TAK-937, a novel cannabinoid receptor agonist, in permanent and thrombotic focal cerebral ischemia in rats: Therapeutic time window, combination with t-PA and efficacy in aged rats (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23791950
Therapeutic Potential of Cannabinoids in Neurodegenerative Disorders: A Selective Review (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23829360
Interplay of cannabinoid 2 (CB2) receptors with nitric oxide synthases, oxidative and nitrative stress, and cell death during remote neurodegeneration (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/22371074
Synthetic Cannabis and Acute Ischemic Stroke (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24119618
Ischemic stroke after use of the synthetic marijuana "spice" (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24212384
Unique effects of compounds active at both cannabinoid and serotonin receptors during stroke (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24323810
Activation of cortical type 2 cannabinoid receptors ameliorates ischemic brain injury (news – 2013) http://www.sciencedaily.com/releases...0221141140.htm
Cannabinoid Trans-Caryophyllene Protects Brain Cells From Ischemia (news – 2013) http://www.medicalnewstoday.com/articles/256799.php
Smoking "spice" associated with stroke in healthy, young adults (news – 2013) http://www.medicalnewstoday.com/releases/269132.php
Cannabinoids: well-suited candidates for the treatment of perinatal brain injury (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4061885/
Cannabinoids: New Promising Agents in the Treatment of Neurological Diseases (link to PDF – 2014) http://www.mdpi.com/1420-3049/19/11/18781
The cannabinoid CB2 receptor agonist GW405833 does not ameliorate brain damage induced by hypoxia-ischemia in rats (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24721671
Roles of fatty acid ethanolamides (FAE) in traumatic and ischemic brain injury (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24874648
Severe rhabdomyolysis and intracranial hemorrhage associated with synthetic cannabinoid: a case report (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25179201
A case of acute cerebral ischemia following inhalation of a synthetic cannabinoid (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25241766
Mn-SOD Upregulation by Electroacupuncture Attenuates Ischemic Oxidative Damage via CB1R-Mediated STAT3 Phosphorylation (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25432886
Cannabinoids in experimental stroke: a systematic review and meta-analysis (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25492113
Protective effects of cannabidiol against hippocampal cell death and cognitive impairment induced by bilateral common carotid artery occlusion in mice (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24532152
Magnolol protects neurons against ischemia injury via the downregulation of p38/MAPK, CHOP and nitrotyrosine. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25038313
Glycogen synthase kinase-3β is involved in electroacupuncture pretreatment via the cannabinoid CB1 receptor in ischemic stroke (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/23943518