Acute administration of cannabidiol in vivo suppresses ischaemia-induced cardiac arrhythmias and reduces infarct size when given at reperfusion. (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2936031/?toolubmed
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3003779/
The cardiac and haemostatic effects of dietary hempseed. (full – 2010) http/www.nutritionandmetabolism.com/content/pdf/1743-7075-7-32.pdf
Endogenous cannabinoid signaling is essential for stress adaptation (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2889099/?toolmcentrez
US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full – 2010) http/www.google.com/patents/US20100158973
Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2962826/?toolubmed
N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels. (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2931560/
Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation (abst – 2010) http/journals.lww.com/ccmjournal/Abstract/2010/12000/Pharmacologically_induced_hypothermia_with.2.aspx
Altered expression of cannabinoid receptors 1 and 2 and activated endocannabinoid system in patients with severe chronic heart failure (abst – 2010) https/www.thieme-connect.com/ejournals/abstract/10.1055/s-0029-1246924
Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst – 2010) http/www.ncbi.nlm.nih.gov/pubmed/19931541
Lab Notes: Pot Has Benefits for Diabetic Hearts (news – 2010) http/www.medpagetoday.com/LabNotes/LabNotes/23853
Inhaled Incense “K2†May Cause Heart Damage (news – 2010) http/drwes.blogspot.com/2010/08/inhaled-incense-k2-may-cause-heart.html
Suicides in other trials led to early termination of trial into effects of weight loss drug rimonabant on cardiovascular outcomes (CRESCENDO study) (news – 2010) http/www.eurekalert.org/pub_releases/2010-08/l-sio081110.php
Pot Compound Mitigates Diabetic Cardiomyopathy (news – 2010) http/www.norml.org/index.cfm?Group_ID=8424
The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00233.x/pdf
Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities (full – 2011) http/www.jpbsonline.org/article.asp?issn=0975-7406;year=2011;volume=3;issue=3;spage=350;epage=36 0;aulast=Cunha
Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3686489/
Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (full – 2011) http/www.sciencedirect.com/science/article/pii/S0091305711002310
Myocardial Infarction Associated With Use of the Synthetic Cannabinoid K2. (full – 2011) http/pediatrics.aappublications.org/content/128/6/e1622.long
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3933972/
Effect of substance abuse on defibrillation threshold in patients with implantable cardioverter-defibrillator. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3022948/
Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors. (abst – 2011) http/heart.bmj.com/content/97/24/e8.9.abstract
Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21294251
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with coronary artery disease in the Chinese Han population. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/22029183
Win 55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker diabetic fatty rats: role of cb2 receptors and cardiac inos/enos expression. (abst – 2011) http/www.unboundmedicine.com/medline/ebm/record/21309057/abstract/Win_55212_2_reduces_cardiac_ischaemia_reperfusion_ injury_in_zucker_diabetic_fatty_rats:_role_of_cb2_ receptors_and_cardiac_inos/enos_expression_
Cannabinoid-2 Receptor Activation Protects against Infarct and Ischemia/Reperfusion Heart Injury. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/22113346
Endocannabinoids and the cardiovascular response to stress. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21708837
Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21802885
The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21893466
Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst – 2011) http/www.unboundmedicine.com/medline/ebm/record/21470162/abstract/Targeting_the_Endocannabinod_System_to_Limit_Myoca rdial_and_Cerebral_Ischemic_and_Reperfusion_Injury _
Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21480765
Marijuana Compounds Hold Promise In Treatment Of Cardiovascular Diseases (news – 2011) http/www.norml.org/index.cfm?Group_ID=8466
Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice (full – 2012) http/eurheartj.oxfordjournals.org/content/33/24/3124.full
Cannabinoids and atherosclerotic coronary heart disease. (full – 2012) http/onlinelibrary.wiley.com/doi/10.1002/clc.21962/pdf
Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors. (full – 2012) http/www.jbc.org/content/early/2012/07/11/jbc.M112.346296.full.pdf+html
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats (full – 2012) http/www.hindawi.com/journals/ijht/2012/647856/
Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies (full – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02042.x/pdf
CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3342253/
Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE) (full – 2012) http/fampra.oxfordjournals.org/content/29/5/521.full
Tolerance to Effects of High-Dose Oral {Delta}9-Tetrahydrocannabinol and Plasma Cannabinoid Concentrations in Male Daily Cannabis Smokers. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3584989/
Cannabinoid receptor CB2 protects against balloon-induced neointima formation. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3774259/
The dose effects of short-term dronabinol (oral THC) maintenance in daily cannabis users. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3546149/
Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22289684
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22138970
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22285599
Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22260337
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22285599
Anandamide enhances expression of heat shock protein 72 to protect against ischemiareperfusion injury in rat heart. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23007622
Cannabis misinterpretation and misadventure in a coroner's court. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23155125
Essential fatty acids and lipid mediators. Endocannabinoids (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22730630
Update on the endocannabinoid-mediated regulation of gelatinase release in arterial wall physiology and atherosclerotic pathophysiology. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23253273
Tachycardia followed by bradycardia after smoking the synthetic cannabinoid “K9″ (news – 2012) http/www.thepoisonreview.com/2012/05/22/tachycardia-followed-by-bradycardia-after-smoking-thesynthetic-cannabinoid-k9/
Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats. (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063449
Is the cardiovascular system a therapeutic target for cannabidiol? (full – 2013) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2012.04351.x/full
Endogenous cannabinoid receptor CB1 activation promotes vascular smooth muscle cell proliferation and neointima formation. (full – 2013) http/www.jlr.org/content/early/2013/03/11/jlr.M035147.long
Modulating the endocannabinoid system in human health and disease: successes and failures (full – 2013) http/onlinelibrary.wiley.com/doi/10.1111/febs.12260/pdf
Anandamide Reduces Intracellular Ca2+ Concentration through Suppression of Na+/Ca2+ Exchanger Current in Rat Cardiac Myocytes (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063386
Surinabant, a selective CB(1) antagonist, inhibits THC-induced central nervous system and heart rate effects in humans. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3703229/
Activation of Cannabinoid Type 2 Receptor by JWH133 Protects Heart Against Ischemia/Reperfusion-Induced Apoptosis. (full – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23711495
Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines (full – 2013) http/eurheartj.oxfordjournals.org/content/34/27/2063.long
Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits. (full – 2013) http/www.actaps.com.cn/qikan/manage/wenzhang/2013-2-03.pdf
Cardiorespiratory control as a function of wake-sleep behavior and diet in mice lacking CB1 cannabinoid receptors (abst – 2013) http/www.fasebj.org/cgi/content/meeting_abstract/27/1_MeetingAbstracts/926.1?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
Role of Central Atypical Cannabinoid Receptor GPR18 in Modulating Cardiovascular Function (abst – 2013) http/www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/663.10?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
An ultra-low dose of tetrahydrocannabinol provides cardioprotection. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23537701
Cardioprotective effect of cannabidiol in rats exposed to doxorubicin toxicity. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23721741
Endocannabinoid system as a potential mechanism for n-3 long-chain polyunsaturated fatty acid mediated cardiovascular protection. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24020800
Common polymorphism in the cannabinoid type 1 receptor gene (CNR1) is associated with microvascular complications in type 2 diabetes. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24075694
Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24120371
Improved Cardiac and Neurologic Outcomes With Postresuscitation Infusion of Cannabinoid Receptor Agonist WIN55, 212-2 Depend on Hypothermia in a Rat Model of Cardiac Arrest. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24346544
A Multiple-Dose, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group QT/QTc Study to Evaluate the Electrophysiologic Effects of THC/CBD Spray (abst – 2013) http/onlinelibrary.wiley.com/doi/10.1002/cpdd.36/abstract
Effects of Acute Stress on Cardiac Endocannabinoids, Lipogenesis, and Inflammation in Rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24367128
Activation of endocannabinoid system in human myocardial hypertrophy (abst – 2013) https/www.thieme-connect.com/ejournals/abstract/10.1055/s-0032-1332632
Pot Smoking Not Linked To Greater Risk Of Death For Those With Coronary Disease (news – 2013) http/norml.org/news/2013/01/31/study-marijuana-smoking-not-associated-with-greater-mortality-riskamong-heart-attack-survivors
New Study: Cannabinoids Protect the Brain and Heart From Injury (news – 2013) http/www.science20.com/news_articles/thc_can_prevent_brain_damage_study-113512
Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. (full – 2014) http/download.springer.com/static/pdf/387/art%253A10.1007%252Fs00210-014-0961-9.pdf?auth66=1396559334_2a7771f3b0767a5092c7c4a570 374992&ext=.pdf
A new face of endocannabinoids in pharmacotherapy. Part I: Protective role of endocannabinoids in hypertension and myocardial infarction. (full – 2014) http/www.jpp.krakow.pl/journal/archive/04_14/pdf/171_04_14_article.pdf
A new face of endocannabinoids in pharmacotherapy. Part II. Role of endocannabinoids in inflammation-derived cardiovascular diseases. (full – 2014) http/www.jpp.krakow.pl/journal/archive/04_14/pdf/183_04_14_article.pdf
Cardiorespiratory Anomalies in Mice Lacking CB1 Cannabinoid Receptors. (full – 2014) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100536
Recurrent myopericarditis as a complication of Marijuana use. (full – 2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3921097/
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http/onlinelibrary.wiley.com/doi/10.1111/bph.12560/full
Cyclooxygenase metabolism mediates vasorelaxation to 2-Arachidonoylglycerol (2-AG) in human mesenteric arteries. (full– 2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3992009/
The Endocannabinoid System - Back to the Scene of Cardiometabolic Risk Factors Control? (full – 2014) https/www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1375653
Mid-ventricular Variant Takotsubo Cardiomyopathy Associated with Cannabinoid Hyperemesis Syndrome: A Case Report. (full – 2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3998230/
A Unique Case of Cardiac Arrest following K2 Abuse. (full – 2014) http/www.hindawi.com/journals/cric/2014/120607/
Effects of cannabinoid receptor type 2 on endogenous myocardial regeneration by activating cardiac progenitor cells in mouse infarcted heart. (link to PDF – 2014) http/life.scichina.com:8082/sciCe/EN/abstract/abstract513395.shtml#
Cannabinoid receptor type 1 activation by arachidonylcyclopropylamide in rat aortic rings causes vasorelaxation involving calcium-activated potassium channel subunit alpha-1 and calcium channel, voltage-dependent, L type, alpha 1C subunit. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24561046
Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24751709
Role of endocannabinoid 2-arachidonoylglycerol in the physiology and pathophysiology of the cardiovascular system. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24934539
The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24980781
Ligand Activation of Cannabinoid Receptors Attenuates Hypertrophy of Neonatal Rat Cardiomyocytes. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24979612
Cannabinoid receptor CB2 prevents development of heart failure in a murine model of pressure overload. (abst – 2014) http/www.freedomwares.ca/p80cannabinoid-receptor-cb2-prevents-development-heart-failure-murinemodel-pressure-overload/
Dual agonism of peripheral cannabinoid CB1/CB2 receptors suppresses cardiac myocyte hypertrophy (abst – 2014) http/www.fasebj.org/content/28/1_Supplement/652.9.abstract?sid=db987fd0-3ef0-4796-aff6-4103f0c84daf
Increased oxidative stress enhances endocannabinoid tone (abst – 2014) http/www.fasebj.org/content/28/1_Supplement/671.13.abstract?sid=db987fd0-3ef0-4796-aff6-4103f0c84daf
Common polymorphism in the cannabinoid type 1 receptor gene (CNR1) is associated with microvascular complications in type 2 diabetes. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24075694
Plasma-Free Fatty Acids, Fatty Acid-Binding Protein 4, and Mortality in Older Adults (from the Cardiovascular Health Study). (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/25073566
Could pot be good for your heart? (news – 2014) http/bgr.com/2014/02/07/marijuana-health-benefits-cardiology/ Pot Smokers Show Less Inflammation (news – 2014) http://news.yahoo.com/pot-smokers-sh...150518763.html
Cannabidiol protects against doxorubicin-induced cardiomyopathy by modulating mitochondrial function and biogenesis (full – 2015)http://static.smallworldlabs.com/mol...14_261_Hao.pdf
Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drug's harm to children and adults, but the scientific evidence is seldom clear-cut (article – 2015) http://onlinelibrary.wiley.com/doi/1...ncy.21516/full
The effect of cannabidiol on ischemia/reperfusion-induced ventricular arrhythmias: the role of adenosine A1 receptors (abst – 2015)http://www.ncbi.nlm.nih.gov/pubmed/24853683
Endocannabinoid-mediated modulation of Gq/11 protein-coupled receptor signaling induced vasoconstriction and hypertension (abst – 2015)http://www.ncbi.nlm.nih.gov/pubmed/25595485
Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity (abst – 2015) http://www.sciencedirect.com/science...03720715000106
Marijuana Chemical Fights Hardened Arteries
http://www.webmd.com/heart-disease/n…dened-arteries
The endogenous cardiac cannabinoid system: a new protective mechanism
http://www.ncbi.nlm.nih.gov/pubmed/16618028
Cardiovascular pharmacology of cannabinoids.
http://www.biowizard.com/story.php?pmid=16596789
Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia
http://www.ingentaconnect.com/conten…20001/00002346
Does Cannabis Hold the Key to Treating Cardiometabolic Disease? (may need free registration)
http://www.medscape.com/viewarticle/525040_print
Cannabinoid Offers Cardioprotection
http://www.norml.org/index.cfm?Group…m_format=print
Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks
http://www.norml.org/index.cfm?Group_ID=6972
Marijuana use, diet, body mass index, and cardiovascular risk factors (may need free registration)
http://www.medscape.com/medline/abstract/16893701
Cannabinoids and cardiovascular disease
http://www.unboundmedicine.com/medli…cal_treatments
Cannabinoids as therapeutic agents in cardiovascular disease
http://www.unboundmedicine.com/medli…_and_illusions
The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol
http://www.unboundmedicine.com/medli…oxide_synthase
Cannabinoids prevented the development of heart failure in animal study
http://www.cannabis-med.org/english/…l.php?id=145#2
Cannabis use not associated with risk factors for diseases of heart and circulation
http://www.cannabis-med.org/english/…l.php?id=225#2
THC protects heart cells in the case of lowered oxygen supply
http://www.cannabis-med.org/english/…l.php?id=212#1
Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the…l_marijua.html
Cardiovascular Effects of Cannabis
http://www.idmu.co.uk/canncardio.htm
Changes in middle cerebral artery velocity after marijuana
http://www.ncbi.nlm.nih.gov/sites/en…&dopt=Abstract
Cannabidiol protects against myocardial ischemic reperfusion injury.
http://marijuana.researchtoday.net/a…/4/12/1404.htm
Function of cannabinoids in heart failure] http://www.unboundmedicine.com/medli…art_failure%5D
Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions
http://www.pubmedcentral.nih.gov/art…tool=pmcentrez
Inhibitor of fatty acid amide hydrolase normalizes cardiovascular function in hypertension without adverse metabolic effects. (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3003779/
The cardiac and haemostatic effects of dietary hempseed. (full – 2010) http/www.nutritionandmetabolism.com/content/pdf/1743-7075-7-32.pdf
Endogenous cannabinoid signaling is essential for stress adaptation (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2889099/?toolmcentrez
US Patent Application 20100158973 - THERAPEUTIC USES OF CANNABIDIOL COMPOUNDS (full – 2010) http/www.google.com/patents/US20100158973
Interaction between anandamide and sphingosine-1-phosphate in mediating vasorelaxation in rat coronary artery (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2962826/?toolubmed
N-arachidonoyl glycine, an endogenous lipid that acts as a vasorelaxant via nitric oxide and large conductance calcium-activated potassium channels. (full – 2010) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC2931560/
Pharmacologically induced hypothermia with cannabinoid receptor agonist WIN55, 212-2 after cardiopulmonary resuscitation (abst – 2010) http/journals.lww.com/ccmjournal/Abstract/2010/12000/Pharmacologically_induced_hypothermia_with.2.aspx
Altered expression of cannabinoid receptors 1 and 2 and activated endocannabinoid system in patients with severe chronic heart failure (abst – 2010) https/www.thieme-connect.com/ejournals/abstract/10.1055/s-0029-1246924
Substantially altered expression pattern of cannabinoid receptor 2 and activated endocannabinoid system in patients with severe heart failure. (abst – 2010) http/www.ncbi.nlm.nih.gov/pubmed/19931541
Lab Notes: Pot Has Benefits for Diabetic Hearts (news – 2010) http/www.medpagetoday.com/LabNotes/LabNotes/23853
Inhaled Incense “K2†May Cause Heart Damage (news – 2010) http/drwes.blogspot.com/2010/08/inhaled-incense-k2-may-cause-heart.html
Suicides in other trials led to early termination of trial into effects of weight loss drug rimonabant on cardiovascular outcomes (CRESCENDO study) (news – 2010) http/www.eurekalert.org/pub_releases/2010-08/l-sio081110.php
Pot Compound Mitigates Diabetic Cardiomyopathy (news – 2010) http/www.norml.org/index.cfm?Group_ID=8424
The potential for clinical use of cannabinoids in treatment of cardiovascular diseases. (full – 2011) http/onlinelibrary.wiley.com/doi/10.1111/j.1755-5922.2010.00233.x/pdf
Endocannabinoid system in cardiovascular disorders - new pharmacotherapeutic opportunities (full – 2011) http/www.jpbsonline.org/article.asp?issn=0975-7406;year=2011;volume=3;issue=3;spage=350;epage=36 0;aulast=Cunha
Variants at the endocannabinoid receptor CB1 gene (CNR1) and insulin sensitivity, type 2 diabetes, and coronary heart disease. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3686489/
Effects of intracisternal administration of cannabidiol on the cardiovascular and behavioral responses to acute restraint stress. (full – 2011) http/www.sciencedirect.com/science/article/pii/S0091305711002310
Myocardial Infarction Associated With Use of the Synthetic Cannabinoid K2. (full – 2011) http/pediatrics.aappublications.org/content/128/6/e1622.long
Is lipid signaling through cannabinoid 2 receptors part of a protective system? (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3062638/
The effects of hempseed meal intake and linoleic acid on Drosophila models of neurodegenerative diseases and hypercholesterolemia. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3933972/
Effect of substance abuse on defibrillation threshold in patients with implantable cardioverter-defibrillator. (full – 2011) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3022948/
Cannabidiol as an anti-arrhythmic, the role of the CB1 receptors. (abst – 2011) http/heart.bmj.com/content/97/24/e8.9.abstract
Distinctive effects of plant protein sources on renal disease progression and associated cardiac hypertrophy in experimental kidney disease. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21294251
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with coronary artery disease in the Chinese Han population. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/22029183
Win 55,212-2 reduces cardiac ischaemia-reperfusion injury in zucker diabetic fatty rats: role of cb2 receptors and cardiac inos/enos expression. (abst – 2011) http/www.unboundmedicine.com/medline/ebm/record/21309057/abstract/Win_55212_2_reduces_cardiac_ischaemia_reperfusion_ injury_in_zucker_diabetic_fatty_rats:_role_of_cb2_ receptors_and_cardiac_inos/enos_expression_
Cannabinoid-2 Receptor Activation Protects against Infarct and Ischemia/Reperfusion Heart Injury. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/22113346
Endocannabinoids and the cardiovascular response to stress. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21708837
Cardiotoxicity associated with the synthetic cannabinoid, K9, with laboratory confirmation. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21802885
The effect of dietary hempseed on atherogenesis and contractile function in aortae from hypercholesterolemic rabbits. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21893466
Targeting the Endocannabinod System to Limit Myocardial and Cerebral Ischemic and Reperfusion Injury. (abst – 2011) http/www.unboundmedicine.com/medline/ebm/record/21470162/abstract/Targeting_the_Endocannabinod_System_to_Limit_Myoca rdial_and_Cerebral_Ischemic_and_Reperfusion_Injury _
Endocannabinoid type 1 receptor gene (CNR1) polymorphisms (rs806381, rs10485170, rs6454674, rs2023239) and cardiovascular risk factors in postmenopausal women. (abst – 2011) http/www.ncbi.nlm.nih.gov/pubmed/21480765
Marijuana Compounds Hold Promise In Treatment Of Cardiovascular Diseases (news – 2011) http/www.norml.org/index.cfm?Group_ID=8466
Deficiency of type 1 cannabinoid receptors worsens acute heart failure induced by pressure overload in mice (full – 2012) http/eurheartj.oxfordjournals.org/content/33/24/3124.full
Cannabinoids and atherosclerotic coronary heart disease. (full – 2012) http/onlinelibrary.wiley.com/doi/10.1002/clc.21962/pdf
Angiotensin II induces vascular endocannabinoid release, which attenuates its vasoconstrictor effect via CB1 cannabinoid receptors. (full – 2012) http/www.jbc.org/content/early/2012/07/11/jbc.M112.346296.full.pdf+html
Metabolic effects of n-3 PUFA as phospholipids are superior to triglycerides in mice fed a high-fat diet: possible role of endocannabinoids. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3372498/
Phytoestrogens Enhance the Vascular Actions of the Endocannabinoid Anandamide in Mesenteric Beds of Female Rats (full – 2012) http/www.hindawi.com/journals/ijht/2012/647856/
Targeting cannabinoid receptor CB2 in cardiovascular disorders: promises and controversies (full – 2012) http/onlinelibrary.wiley.com/doi/10.1111/j.1476-5381.2012.02042.x/pdf
CNR1 genotype influences HDL-cholesterol response to change in dietary fat intake. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3342253/
Rimonabant improves obesity but not the overall cardiovascular risk and quality of life; results from CARDIO-REDUSE (CArdiometabolic Risk reDuctIOn by Rimonabant: the Effectiveness in Daily practice and its USE) (full – 2012) http/fampra.oxfordjournals.org/content/29/5/521.full
Tolerance to Effects of High-Dose Oral {Delta}9-Tetrahydrocannabinol and Plasma Cannabinoid Concentrations in Male Daily Cannabis Smokers. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3584989/
Cannabinoid receptor CB2 protects against balloon-induced neointima formation. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3774259/
The dose effects of short-term dronabinol (oral THC) maintenance in daily cannabis users. (full – 2012) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3546149/
Cannabinoid 1 (CB1) receptor mediates WIN55, 212-2 induced hypothermia and improved survival in a rat post-cardiac arrest model. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22289684
G1359A polymorphism in the cannabinoid receptor-1 gene is associated with the presence of coronary artery disease in patients with type 2 diabetes. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22138970
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22285599
Subjective, cognitive and cardiovascular dose-effect profile of nabilone and dronabinol in marijuana smokers. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22260337
Vascular metabolism of anandamide to arachidonic acid affects myogenic constriction in response to intraluminal pressure elevation. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22285599
Anandamide enhances expression of heat shock protein 72 to protect against ischemiareperfusion injury in rat heart. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23007622
Cannabis misinterpretation and misadventure in a coroner's court. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23155125
Essential fatty acids and lipid mediators. Endocannabinoids (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/22730630
Update on the endocannabinoid-mediated regulation of gelatinase release in arterial wall physiology and atherosclerotic pathophysiology. (abst – 2012) http/www.ncbi.nlm.nih.gov/pubmed/23253273
Tachycardia followed by bradycardia after smoking the synthetic cannabinoid “K9″ (news – 2012) http/www.thepoisonreview.com/2012/05/22/tachycardia-followed-by-bradycardia-after-smoking-thesynthetic-cannabinoid-k9/
Reduced endothelium-dependent relaxation to anandamide in mesenteric arteries from young obese zucker rats. (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063449
Is the cardiovascular system a therapeutic target for cannabidiol? (full – 2013) http/onlinelibrary.wiley.com/doi/10.1111/j.1365-2125.2012.04351.x/full
Endogenous cannabinoid receptor CB1 activation promotes vascular smooth muscle cell proliferation and neointima formation. (full – 2013) http/www.jlr.org/content/early/2013/03/11/jlr.M035147.long
Modulating the endocannabinoid system in human health and disease: successes and failures (full – 2013) http/onlinelibrary.wiley.com/doi/10.1111/febs.12260/pdf
Anandamide Reduces Intracellular Ca2+ Concentration through Suppression of Na+/Ca2+ Exchanger Current in Rat Cardiac Myocytes (full – 2013) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0063386
Surinabant, a selective CB(1) antagonist, inhibits THC-induced central nervous system and heart rate effects in humans. (full – 2013) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3703229/
Activation of Cannabinoid Type 2 Receptor by JWH133 Protects Heart Against Ischemia/Reperfusion-Induced Apoptosis. (full – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23711495
Improvement in coronary circulatory function in morbidly obese individuals after gastric bypass-induced weight loss: relation to alterations in endocannabinoids and adipocytokines (full – 2013) http/eurheartj.oxfordjournals.org/content/34/27/2063.long
Inhibitory effects of endocannabinoid on the action potential of pacemaker cells in sinoatrial nodes of rabbits. (full – 2013) http/www.actaps.com.cn/qikan/manage/wenzhang/2013-2-03.pdf
Cardiorespiratory control as a function of wake-sleep behavior and diet in mice lacking CB1 cannabinoid receptors (abst – 2013) http/www.fasebj.org/cgi/content/meeting_abstract/27/1_MeetingAbstracts/926.1?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
Role of Central Atypical Cannabinoid Receptor GPR18 in Modulating Cardiovascular Function (abst – 2013) http/www.fasebj.org/cgi/content/meeting_abstract/26/1_MeetingAbstracts/663.10?sid=eea722c0-971c-4daa-8b8c-38c0c63c19ad
An ultra-low dose of tetrahydrocannabinol provides cardioprotection. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23537701
Cardioprotective effect of cannabidiol in rats exposed to doxorubicin toxicity. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/23721741
Endocannabinoid system as a potential mechanism for n-3 long-chain polyunsaturated fatty acid mediated cardiovascular protection. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24020800
Common polymorphism in the cannabinoid type 1 receptor gene (CNR1) is associated with microvascular complications in type 2 diabetes. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24075694
Cannabinoids alter endothelial function in the Zucker rat model of type 2 diabetes. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24120371
Improved Cardiac and Neurologic Outcomes With Postresuscitation Infusion of Cannabinoid Receptor Agonist WIN55, 212-2 Depend on Hypothermia in a Rat Model of Cardiac Arrest. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24346544
A Multiple-Dose, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group QT/QTc Study to Evaluate the Electrophysiologic Effects of THC/CBD Spray (abst – 2013) http/onlinelibrary.wiley.com/doi/10.1002/cpdd.36/abstract
Effects of Acute Stress on Cardiac Endocannabinoids, Lipogenesis, and Inflammation in Rats. (abst – 2013) http/www.ncbi.nlm.nih.gov/pubmed/24367128
Activation of endocannabinoid system in human myocardial hypertrophy (abst – 2013) https/www.thieme-connect.com/ejournals/abstract/10.1055/s-0032-1332632
Pot Smoking Not Linked To Greater Risk Of Death For Those With Coronary Disease (news – 2013) http/norml.org/news/2013/01/31/study-marijuana-smoking-not-associated-with-greater-mortality-riskamong-heart-attack-survivors
New Study: Cannabinoids Protect the Brain and Heart From Injury (news – 2013) http/www.science20.com/news_articles/thc_can_prevent_brain_damage_study-113512
Mechanisms of endothelium-dependent relaxation evoked by anandamide in isolated human pulmonary arteries. (full – 2014) http/download.springer.com/static/pdf/387/art%253A10.1007%252Fs00210-014-0961-9.pdf?auth66=1396559334_2a7771f3b0767a5092c7c4a570 374992&ext=.pdf
A new face of endocannabinoids in pharmacotherapy. Part I: Protective role of endocannabinoids in hypertension and myocardial infarction. (full – 2014) http/www.jpp.krakow.pl/journal/archive/04_14/pdf/171_04_14_article.pdf
A new face of endocannabinoids in pharmacotherapy. Part II. Role of endocannabinoids in inflammation-derived cardiovascular diseases. (full – 2014) http/www.jpp.krakow.pl/journal/archive/04_14/pdf/183_04_14_article.pdf
Cardiorespiratory Anomalies in Mice Lacking CB1 Cannabinoid Receptors. (full – 2014) http/www.plosone.org/article/info%3Adoi%2F10.1371%2Fjournal.pone.0100536
Recurrent myopericarditis as a complication of Marijuana use. (full – 2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3921097/
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http/onlinelibrary.wiley.com/doi/10.1111/bph.12560/full
Cyclooxygenase metabolism mediates vasorelaxation to 2-Arachidonoylglycerol (2-AG) in human mesenteric arteries. (full– 2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3992009/
The Endocannabinoid System - Back to the Scene of Cardiometabolic Risk Factors Control? (full – 2014) https/www.thieme-connect.com/products/ejournals/html/10.1055/s-0034-1375653
Mid-ventricular Variant Takotsubo Cardiomyopathy Associated with Cannabinoid Hyperemesis Syndrome: A Case Report. (full – 2014) http/www.ncbi.nlm.nih.gov/pmc/articles/PMC3998230/
A Unique Case of Cardiac Arrest following K2 Abuse. (full – 2014) http/www.hindawi.com/journals/cric/2014/120607/
Effects of cannabinoid receptor type 2 on endogenous myocardial regeneration by activating cardiac progenitor cells in mouse infarcted heart. (link to PDF – 2014) http/life.scichina.com:8082/sciCe/EN/abstract/abstract513395.shtml#
Cannabinoid receptor type 1 activation by arachidonylcyclopropylamide in rat aortic rings causes vasorelaxation involving calcium-activated potassium channel subunit alpha-1 and calcium channel, voltage-dependent, L type, alpha 1C subunit. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24561046
Cannabinoid and lipid-mediated vasorelaxation in retinal microvasculature. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24751709
Role of endocannabinoid 2-arachidonoylglycerol in the physiology and pathophysiology of the cardiovascular system. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24934539
The endocannabinoid-CB2 receptor axis protects the ischemic heart at the early stage of cardiomyopathy. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24980781
Ligand Activation of Cannabinoid Receptors Attenuates Hypertrophy of Neonatal Rat Cardiomyocytes. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24979612
Cannabinoid receptor CB2 prevents development of heart failure in a murine model of pressure overload. (abst – 2014) http/www.freedomwares.ca/p80cannabinoid-receptor-cb2-prevents-development-heart-failure-murinemodel-pressure-overload/
Dual agonism of peripheral cannabinoid CB1/CB2 receptors suppresses cardiac myocyte hypertrophy (abst – 2014) http/www.fasebj.org/content/28/1_Supplement/652.9.abstract?sid=db987fd0-3ef0-4796-aff6-4103f0c84daf
Increased oxidative stress enhances endocannabinoid tone (abst – 2014) http/www.fasebj.org/content/28/1_Supplement/671.13.abstract?sid=db987fd0-3ef0-4796-aff6-4103f0c84daf
Common polymorphism in the cannabinoid type 1 receptor gene (CNR1) is associated with microvascular complications in type 2 diabetes. (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/24075694
Plasma-Free Fatty Acids, Fatty Acid-Binding Protein 4, and Mortality in Older Adults (from the Cardiovascular Health Study). (abst – 2014) http/www.ncbi.nlm.nih.gov/pubmed/25073566
Could pot be good for your heart? (news – 2014) http/bgr.com/2014/02/07/marijuana-health-benefits-cardiology/ Pot Smokers Show Less Inflammation (news – 2014) http://news.yahoo.com/pot-smokers-sh...150518763.html
Cannabidiol protects against doxorubicin-induced cardiomyopathy by modulating mitochondrial function and biogenesis (full – 2015)http://static.smallworldlabs.com/mol...14_261_Hao.pdf
Cannabis conundrum: Evidence of harm?: Opposition to marijuana use is often rooted in arguments about the drug's harm to children and adults, but the scientific evidence is seldom clear-cut (article – 2015) http://onlinelibrary.wiley.com/doi/1...ncy.21516/full
The effect of cannabidiol on ischemia/reperfusion-induced ventricular arrhythmias: the role of adenosine A1 receptors (abst – 2015)http://www.ncbi.nlm.nih.gov/pubmed/24853683
Endocannabinoid-mediated modulation of Gq/11 protein-coupled receptor signaling induced vasoconstriction and hypertension (abst – 2015)http://www.ncbi.nlm.nih.gov/pubmed/25595485
Direct activation of the proposed anti-diabetic receptor, GPR119 in cardiomyoblasts decreases markers of muscle metabolic activity (abst – 2015) http://www.sciencedirect.com/science...03720715000106
Marijuana Chemical Fights Hardened Arteries
http://www.webmd.com/heart-disease/n…dened-arteries
The endogenous cardiac cannabinoid system: a new protective mechanism
http://www.ncbi.nlm.nih.gov/pubmed/16618028
Cardiovascular pharmacology of cannabinoids.
http://www.biowizard.com/story.php?pmid=16596789
Delta-9-tetrahydrocannabinol protects cardiac cells from hypoxia
http://www.ingentaconnect.com/conten…20001/00002346
Does Cannabis Hold the Key to Treating Cardiometabolic Disease? (may need free registration)
http://www.medscape.com/viewarticle/525040_print
Cannabinoid Offers Cardioprotection
http://www.norml.org/index.cfm?Group…m_format=print
Heavy Cannabis Use Not Independently Associated With Cardiovascular Risks
http://www.norml.org/index.cfm?Group_ID=6972
Marijuana use, diet, body mass index, and cardiovascular risk factors (may need free registration)
http://www.medscape.com/medline/abstract/16893701
Cannabinoids and cardiovascular disease
http://www.unboundmedicine.com/medli…cal_treatments
Cannabinoids as therapeutic agents in cardiovascular disease
http://www.unboundmedicine.com/medli…_and_illusions
The in vitro and in vivo cardiovascular effects of {Delta}9-tetrahydrocannabinol
http://www.unboundmedicine.com/medli…oxide_synthase
Cannabinoids prevented the development of heart failure in animal study
http://www.cannabis-med.org/english/…l.php?id=145#2
Cannabis use not associated with risk factors for diseases of heart and circulation
http://www.cannabis-med.org/english/…l.php?id=225#2
THC protects heart cells in the case of lowered oxygen supply
http://www.cannabis-med.org/english/…l.php?id=212#1
Medical marijuana: study shows that THC slows atherosclerosis
http://thenexthurrah.typepad.com/the…l_marijua.html
Cardiovascular Effects of Cannabis
http://www.idmu.co.uk/canncardio.htm
Changes in middle cerebral artery velocity after marijuana
http://www.ncbi.nlm.nih.gov/sites/en…&dopt=Abstract
Cannabidiol protects against myocardial ischemic reperfusion injury.
http://marijuana.researchtoday.net/a…/4/12/1404.htm
Function of cannabinoids in heart failure] http://www.unboundmedicine.com/medli…art_failure%5D
Cannabinoids as therapeutic agents in cardiovascular disease: a tale of passions and illusions
http://www.pubmedcentral.nih.gov/art…tool=pmcentrez