Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16310817
A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2- Arachidonoylglycerol (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692834/
Organophosphate-Sensitive Lipases Modulate Brain Lysophospholipids, Ether Lipids and Endocannabinoids (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582404/
Activation of the endocannabinoid system by organophosphorus nerve agents (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597283/
Presence of functional cannabinoid receptors in human endocrine pancreas. (abst – 2008) http://www.frontiersin.org/publications/18092149
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. (full – 2009) http://jpet.aspetjournals.org/content/331/2/591.long
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarizationinduced suppression of excitation in autaptic hippocampal neurons. (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784730/
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/
Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/arti...report=classic
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224879/
Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hemorrhages in mice. (full – 2011) http://jpet.aspetjournals.org/conten...10.175778.long
The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2â€arachidonoylglycerol signalling through cannabinoid receptors (full – 2011) http://onlinelibrary.wiley.com/doi/1...1.02280.x/full
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249428/
Scripps Research Scientists Discover Inflammation Is Controlled Differently in Brain and Other Tissues (news – 2011) http://www.alphagalileo.org/ViewItem...CultureCode=en
Intrinsic Up-Regulation of 2-AG Favors an Area Specific Neuronal Survival in Different In Vitro Models of Neuronal Damage. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527460/
Dynamic changes to the endocannabinoid system in models of chronic pain (full – 2012) http://rstb.royalsocietypublishing.o...f-857201f5e069
Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345137/
The endocannabinoid system: an overview (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303140/
Monoacylglycerol lipase is a new therapeutic target for Alzheimer’s disease (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513645/
Endocannabinoid signaling in female reproduction. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382454/
Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525790/
Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat (full – 2012) http://onlinelibrary.wiley.com/doi/1...2.02179.x/full
Monoacylglycerol lipase – a target for drug development? (full – 2012) http://onlinelibrary.wiley.com/doi/1...12.01950.x/pdf
Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-α Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652685/
Equipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase - Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480564/
Expression and function of monoacylglycerol lipase in mouse β-cells and human islets of Langerhans. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22739267
Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22127371
Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808422/
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788575/
Parsing the players: 2-AG synthesis and degradation in the CNS (full – 2013) http://onlinelibrary.wiley.com/doi/1...bph.12411/full
Neuregulin-1 Impairs the Long-term Depression of Hippocampal Inhibitory Synapses by Facilitating the Degradation of Endocannabinoid 2-AG. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776056/
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717616/
Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854987/
Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. (full – 2013) http://www.pnas.org/content/110/43/17558.long
Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Anti-Withdrawal Effects in Morphine-Dependent Mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23303065
Therapeutic potential of monoacylglycerol lipase inhibitors. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594462/
Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine inflammatory pain model. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24384256
In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: Antinociceptive activity without cannabimimetic side effects. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23848221
(4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23455058
Aging modifies the enzymatic activities involved in 2-arachidonoylglycerol metabolism. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23281018
Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde synaptic suppression: evidence for on-demand biosynthesis of 2-arachidonoylglycerol. (abst - 2013) http://www.ncbi.nlm.nih.gov/pubmed/23858009
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http://onlinelibrary.wiley.com/doi/1...bph.12560/full
Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953590/
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective. (full– 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979158/
The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109781/
The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995979/
The expression of cannabinoid receptor 1 is significantly increased in atopic patients (full – 2014) http://www.jacionline.org/article/S0...936-9/fulltext
Localization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLα) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus. (full – 2014) http://journal.frontiersin.org/Journ...014.00056/full
Cannabinoids as therapeutic agents in cancer: current status and future implications. (link to PDF- 2014) http://www.impactjournals.com/oncota...e&op=view&path[]=2233
Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24476943
Brain regional cannabinoid CB1 receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice (abst – 2014) http://www.sciencedirect.com/science...28098713003497
Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1-and 2-monoacylglycerols and selectively impairs inhibitor potency. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24368842
No more pain upon Gq -protein-coupled receptor activation: role of endocannabinoids. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24494686
Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s). (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24361246
Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24508383
Targeting the cannabinoid system for pain relief? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24529672
Endocannabinoid-Hydrolysing Enzymes in the Post-Mortem Cerebellum of Humans Affected by Hereditary Autosomal Dominant Ataxias. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24642775
The Role of Monoacylglycerol Lipase (MAGL) in the Cancer Progress. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24633487
Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24676249
Functionalization of β-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid System. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24831513
Identification and characterization of a new reversible MAGL inhibitor. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24853323
Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24858366
Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24906199
The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24911644
Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24915981
Endocannabinoid-hydrolysing enzymes in the post-mortem cerebellum of humans affected by hereditary autosomal dominant ataxias. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24642775
The endocannabinoid system is altered in the post-mortem prefrontal cortex of alcoholic subjects (abst – 2014) http://onlinelibrary.wiley.com/doi/1...12160/abstract
Endocannabinoid modulation by FAAH and MAGL within the analgesic circuitry of the periaqueductal grey. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25041240
Endocannabinoid Regulation in Human Endometrium Across the Menstrual Cycle (abst – 2014) http://rsx.sagepub.com/content/early...33730.abstract
A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2- Arachidonoylglycerol (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692834/
Organophosphate-Sensitive Lipases Modulate Brain Lysophospholipids, Ether Lipids and Endocannabinoids (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582404/
Activation of the endocannabinoid system by organophosphorus nerve agents (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597283/
Presence of functional cannabinoid receptors in human endocrine pancreas. (abst – 2008) http://www.frontiersin.org/publications/18092149
Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhibitor 4-nitrophenyl 4-(dibenzo[d][1,3]dioxol-5-yl(hydroxy)methyl)piperidine-1-carboxylate (JZL184) Enhances retrograde endocannabinoid signaling. (full – 2009) http://jpet.aspetjournals.org/content/331/2/591.long
Monoacylglycerol lipase limits the duration of endocannabinoid-mediated depolarizationinduced suppression of excitation in autaptic hippocampal neurons. (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2784730/
The endocannabinoid system of the skin in health and disease: novel perspectives and therapeutic opportunities (full – 2009) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2757311/
Characterization of tunable piperidine and piperazine carbamates as inhibitors of endocannabinoid hydrolases (full – 2010) http://www.ncbi.nlm.nih.gov/pmc/arti...report=classic
Genetic deletion of monoacylglycerol lipase alters endocannabinoid-mediated retrograde synaptic depression in the cerebellum. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224879/
Inhibition of monoacylglycerol lipase (MAGL) attenuates NSAID-induced gastric hemorrhages in mice. (full – 2011) http://jpet.aspetjournals.org/conten...10.175778.long
The serine hydrolases MAGL, ABHD6 and ABHD12 as guardians of 2â€arachidonoylglycerol signalling through cannabinoid receptors (full – 2011) http://onlinelibrary.wiley.com/doi/1...1.02280.x/full
Endocannabinoid hydrolysis generates brain prostaglandins that promote neuroinflammation (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3249428/
Scripps Research Scientists Discover Inflammation Is Controlled Differently in Brain and Other Tissues (news – 2011) http://www.alphagalileo.org/ViewItem...CultureCode=en
Intrinsic Up-Regulation of 2-AG Favors an Area Specific Neuronal Survival in Different In Vitro Models of Neuronal Damage. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3527460/
Dynamic changes to the endocannabinoid system in models of chronic pain (full – 2012) http://rstb.royalsocietypublishing.o...f-857201f5e069
Inhibition of recombinant human carboxylesterase 1 and 2 and monoacylglycerol lipase by chlorpyrifos oxon, paraoxon and methyl paraoxon. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3345137/
The endocannabinoid system: an overview (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3303140/
Monoacylglycerol lipase is a new therapeutic target for Alzheimer’s disease (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3513645/
Endocannabinoid signaling in female reproduction. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3382454/
Alterations in endocannabinoid tone following chemotherapy-induced peripheral neuropathy: effects of endocannabinoid deactivation inhibitors targeting fatty-acid amide hydrolase and monoacylglycerol lipase in comparison to reference analgesics following cisplatin treatment. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3525790/
Spinal administration of the monoacylglycerol lipase inhibitor JZL184 produces robust inhibitory effects on nociceptive processing and the development of central sensitization in the rat (full – 2012) http://onlinelibrary.wiley.com/doi/1...2.02179.x/full
Monoacylglycerol lipase – a target for drug development? (full – 2012) http://onlinelibrary.wiley.com/doi/1...12.01950.x/pdf
Activation of Type 5 Metabotropic Glutamate Receptors and Diacylglycerol Lipase-α Initiates 2-Arachidonoylglycerol Formation and Endocannabinoid-Mediated Analgesia. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3652685/
Equipotent Inhibition of Fatty Acid Amide Hydrolase and Monoacylglycerol Lipase - Dual Targets of the Endocannabinoid System to Protect against Seizure Pathology. (full – 2012) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3480564/
Expression and function of monoacylglycerol lipase in mouse β-cells and human islets of Langerhans. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22739267
Dual inhibition of MAGL and type II topoisomerase by N-phenylmaleimides as a potential strategy to reduce neuroblastoma cell growth. (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22127371
Monoacylglycerol Lipase (MAGL) Inhibition Attenuates Acute Lung Injury in Mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3808422/
Substrate-selective COX-2 inhibition decreases anxiety via endocannabinoid activation. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3788575/
Parsing the players: 2-AG synthesis and degradation in the CNS (full – 2013) http://onlinelibrary.wiley.com/doi/1...bph.12411/full
Neuregulin-1 Impairs the Long-term Depression of Hippocampal Inhibitory Synapses by Facilitating the Degradation of Endocannabinoid 2-AG. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3776056/
The monoacylglycerol lipase inhibitor JZL184 suppresses inflammatory pain in the mouse carrageenan model. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3717616/
Astroglial CB1 cannabinoid receptors regulate leptin signaling in mouse brain astrocytes. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3854987/
Implication of the anti-inflammatory bioactive lipid prostaglandin D2-glycerol ester in the control of macrophage activation and inflammation by ABHD6. (full – 2013) http://www.pnas.org/content/110/43/17558.long
Dual Inhibition of Endocannabinoid Catabolic Enzymes Produces Enhanced Anti-Withdrawal Effects in Morphine-Dependent Mice. (full – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23303065
Therapeutic potential of monoacylglycerol lipase inhibitors. (full – 2013) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3594462/
Actions of the dual FAAH/MAGL inhibitor JZL195 in a murine inflammatory pain model. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/24384256
In vivo characterization of the highly selective monoacylglycerol lipase inhibitor KML29: Antinociceptive activity without cannabimimetic side effects. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23848221
(4-Phenoxyphenyl)tetrazolecarboxamides and related compounds as dual inhibitors of fatty acid amide hydrolase (FAAH) and monoacylglycerol lipase (MAGL). (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23455058
Aging modifies the enzymatic activities involved in 2-arachidonoylglycerol metabolism. (abst – 2013) http://www.ncbi.nlm.nih.gov/pubmed/23281018
Acute inhibition of diacylglycerol lipase blocks endocannabinoid-mediated retrograde synaptic suppression: evidence for on-demand biosynthesis of 2-arachidonoylglycerol. (abst - 2013) http://www.ncbi.nlm.nih.gov/pubmed/23858009
Vascular targets for cannabinoids: animal and human studies. (full – 2014) http://onlinelibrary.wiley.com/doi/1...bph.12560/full
Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953590/
2012 Division of Medicinal Chemistry Award Address: Trekking the Cannabinoid Road: A Personal Perspective. (full– 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4064474/
Heterogeneous presynaptic distribution of monoacylglycerol lipase, a multipotent regulator of nociceptive circuits in the mouse spinal cord. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3979158/
The influence of monoacylglycerol lipase inhibition upon the expression of epidermal growth factor receptor in human PC-3 prostate cancer cells (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4109781/
The effects of obesity, diabetes and metabolic syndrome on the hydrolytic enzymes of the endocannabinoid system in animal and human adipocytes. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3995979/
The expression of cannabinoid receptor 1 is significantly increased in atopic patients (full – 2014) http://www.jacionline.org/article/S0...936-9/fulltext
Localization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLα) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus. (full – 2014) http://journal.frontiersin.org/Journ...014.00056/full
Cannabinoids as therapeutic agents in cancer: current status and future implications. (link to PDF- 2014) http://www.impactjournals.com/oncota...e&op=view&path[]=2233
Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24476943
Brain regional cannabinoid CB1 receptor signalling and alternative enzymatic pathways for 2-arachidonoylglycerol generation in brain sections of diacylglycerol lipase deficient mice (abst – 2014) http://www.sciencedirect.com/science...28098713003497
Mutation of cys242 of human monoacylglycerol lipase disrupts balanced hydrolysis of 1-and 2-monoacylglycerols and selectively impairs inhibitor potency. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24368842
No more pain upon Gq -protein-coupled receptor activation: role of endocannabinoids. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24494686
Organophosphate agents induce plasma hypertriglyceridemia in mouse via single or dual inhibition of the endocannabinoid hydrolyzing enzyme(s). (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24361246
Dexamethasone alleviates motion sickness in rats in part by enhancing the endocannabinoid system. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24508383
Targeting the cannabinoid system for pain relief? (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24529672
Endocannabinoid-Hydrolysing Enzymes in the Post-Mortem Cerebellum of Humans Affected by Hereditary Autosomal Dominant Ataxias. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24642775
The Role of Monoacylglycerol Lipase (MAGL) in the Cancer Progress. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24633487
Chemical approaches to therapeutically target the metabolism and signaling of the endocannabinoid 2-AG and eicosanoids (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24676249
Functionalization of β-Caryophyllene Generates Novel Polypharmacology in the Endocannabinoid System. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24831513
Identification and characterization of a new reversible MAGL inhibitor. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24853323
Endocannabinoid contribution to Δ9-tetrahydrocannabinol discrimination in rodents. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24858366
Augmented tonic pain-related behavior in knockout mice lacking monoacylglycerol lipase, a major degrading enzyme for the endocannabinoid 2-arachidonoylglycerol. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24906199
The dual FAAH/MAGL inhibitor JZL195 has enhanced effects on endocannabinoid transmission and motor behavior in rats as compared to those of the MAGL inhibitor JZL184. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24911644
Attenuation of serotonin-induced itch responses by inhibition of endocannabinoid degradative enzymes, fatty acid amide hydrolase and monoacylglycerol lipase. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24915981
Endocannabinoid-hydrolysing enzymes in the post-mortem cerebellum of humans affected by hereditary autosomal dominant ataxias. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/24642775
The endocannabinoid system is altered in the post-mortem prefrontal cortex of alcoholic subjects (abst – 2014) http://onlinelibrary.wiley.com/doi/1...12160/abstract
Endocannabinoid modulation by FAAH and MAGL within the analgesic circuitry of the periaqueductal grey. (abst – 2014) http://www.ncbi.nlm.nih.gov/pubmed/25041240
Endocannabinoid Regulation in Human Endometrium Across the Menstrual Cycle (abst – 2014) http://rsx.sagepub.com/content/early...33730.abstract