p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells (full – 2005)http://www.sciencedirect.com/science...14579305010057
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor (full – 2006)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616976/
The CB2 cannabinoid receptor si...
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SR-144528
- 1 post
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MAGL / MGL / MONOACYLGLYCEROL LIPASE > 2006-2014
Monoacylglycerol lipase inhibition by organophosphorus compounds leads to elevation of brain 2-arachidonoylglycerol and the associated hypomotility in mice. (abst – 2006) http://www.ncbi.nlm.nih.gov/pubmed/16310817
A Comprehensive Profile of Brain Enzymes that Hydrolyze the Endocannabinoid 2- Arachidonoylglycerol (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2692834/
Organophosphate-Sensitive Lipases Modulate Brain Lysophospholipids, Ether Lipids and Endocannabinoids (full – 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2582404/
Activation of the endocannabinoid system by organophosphorus nerve agents (full - 2008) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2597283/
Presence of functional cannabinoid receptors in human endocrine pancreas. (abst – 2008) http://www.frontiersin.org/publications/18092149 Blockade of 2-arachidonoylglycerol hydrolysis by selective monoacylglycerol lipase inhi...
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L-a-LYSOPHOSPHATIDYLINOSITOL > 2009-2013
The GPR55 ligand L-alpha-lysophosphatidylinositol promotes RhoA-dependent Ca2+ signaling and NFAT activation. (full – 2009) http://www.fasebj.org/content/23/1/183.long GPR55 ligands promote receptor coupl...
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HEMOPRESIN > 2007-2014
Hemopressin is an inverse agonist of CB1 cannabinoid receptors (full – 2007) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2154475/ Novel endogenous peptide agonists of cannabinoid receptors (full – 2009)...
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FABP / FATTY ACID BINDING PROTEINS > 2014
Inhibition of Fatty Acid binding proteins elevates brain anandamide levels and produces analgesia. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3976407/ Inv...
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FAAH / FATTY ACID AMIDE HYDROLASE > 2011-2014
Arachidonoyl ethanolamide (AEA)-induced apoptosis is mediated by J-series prostaglandins and is enhanced by fatty acid amide hydrolase (FAAH) blockade. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...ihms275514.pdf
Endocannabinoid regulation of acute and protracted nicotine withdrawal: effect of FAAH inhibition. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/arti...0/?tool=pubmed
A catalytically silent FAAH-1 variant drives anandamide transport in neurons. (full – 2011) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245783/
The activity of the endocannabinoid metabolising enzyme fatty acid amide hydrolase in subcutaneous adipocytes correlates with BMI in metabolically healthy humans (full – 2011) http://www.lipidworld.com/content/10/1/129
Dual inhibition of alpha/beta hydrolase domain 6 and fatty acid amide hydrolase increases endocannabinoid levels in neurons. (full – 2011) http://www.jbc.org/content/early/201...10.202853.long
Fatty acid amide hydrolase blockade attenuates the development of collagen-induced arthritis and related thermal hyperalgesia in mice. (abst – 2011) http://www.ncbi.nlm.nih.gov/pubmed/21740924 Endocannabinoid regulation of acute and protracted nicotine wi...
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ENDOCANNABINOID SYSTEM* > 2014
Δ(9)-THC and N-arachidonoyl glycine regulate BV-2 microglial morphology and cytokine release plasticity: implications for signaling at GPR18. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3877838/
Endocannabinoid Modulation of Cortical Up-States and NREM Sleep (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919802/
Involvement of the Cannabinoid CB1 Receptor in Modulation of Dopamine Output in the Prefrontal Cortex
Associated with Food Restriction in Rats. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3954872/
Endocannabinoids are Involved in Male Vertebrate Reproduction: Regulatory Mechanisms at Central and Gonadal Level. (full – 2014) http://journal.frontiersin.org/Journ...014.00054/full
Prefrontal deficits in a murine model overexpressing the down syndrome candidate gene dyrk1a. (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3953590/
The in vitro GcMAF effects on endocannabinoid system transcriptionomics, receptor formation, and cell activity of autism-derived macrophages. (full – 2014) http://www.ncbi.nlm.nih...
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SPICE - NEWS
Synthetic cannabis mimic found in herbal incense (news – 2009) http://www.rsc.org/chemistryworld/Ne...y/15010901.asp
Inhaled Incense “K2†May Cause Heart Damage (news – 2010) http://drwes.blogspot.com/2010/08/in...use-heart.html
The New Cannabinoids (news – 2010) http://www.wellsphere.com/drug-addic...inoids/1247426
Outlawing ‘Legal Highs:’ Can Emergency Bans Hinder Drug Development? (news – 2011) http://health...
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SPICE - STUDIES
'Crazy Monkey' Poisons Man and Dog: Human and canine seizures due to PB-22, a novel synthetic cannabinoid (full – 2014)http://informahealthcare.com/doi/ful...50.2014.925562
Emerging Drugs of Abuse: Clinical and Legal Considerations (full – 2014) http://rimed.org/rimedicaljournal/20...psych-aoun.pdf Hair analy...
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SR-144528
p38 MAPK is involved in CB2 receptor-induced apoptosis of human leukaemia cells (full – 2005)http://www.sciencedirect.com/science...14579305010057
Vasorelaxant effects of oleamide in rat small mesenteric artery indicate action at a novel cannabinoid receptor (full – 2006)http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1616976/ The CB2 cannabinoid receptor si...
- 1 post
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S-444823
Discovery of S-444823, a potent CB1/CB2 dual agonist as an antipruritic agent (abst – 2012) http://www.ncbi.nlm.nih.gov/pubmed/22421019
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SAB-378
CB1 receptors mediate the analgesic effects of cannabinoids on colorectal distension-induced visceral pain in rodents (full – 2007)http://www.jneurosci.org/content/29/5/1554.long ...
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SAD-448
Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists (abst – 2013)http://www...
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ENDOCANNABINOIDS* > 2014
Endocannabinoid Modulation of Cortical Up-States and NREM Sleep (full – 2014) http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3919802/
Antidepressants and Changes in Concentration of Endocannabinoids and Nacylethanolamines in Rat Brain Structures. (full – 2014) http://download.springer.com/static/...13e4a&ext=.pdf Quantification of an...
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RWJ-400065
Control of spasticity in a multiple sclerosis model is mediated by CB1, not CB2, cannabinoid receptors (full - 2007)http://www.ncbi.nlm.nih.gov/pmc/a...
- 1 post